Cirrhosis Flashcards
1
Q
What is Cirrhosis
A
It is the final stage of chronic liver disease
Leading cause of death
2
Q
Cause of cirrhosis
A
Alcoholism (60-70%) Hepatitis Biliary disease Metb disorders (Wilsons disease) Drugs
3
Q
What is the idiopathic form of cirrhosis
A
Cryptogenic cirrhosis
4
Q
Patho of cirrhosis
A
Hepatocyte necrosis> cells regenerate bound by fibrous tissue
Diffuse fibrosis replace functional tissue
Vessel constriction> impeded perf>portal HTN> fluid shift > ascites
Biliary duct constriction > bile stasis
Decreased metb waste clearance> liver failure
5
Q
Mnfts of cirrhosis
A
Vary based on stage of liver failure
Anorexia, weakness, wt loss
Hepatomegaly, jaundice
6
Q
Complications of cirrhosis
A
Portal HTN and ascites
Varix dilate
Varicies rupture
Splenomegaly
7
Q
Tx of cirrhosis
A
Facilitate regeneration
- diet (small meals, high calorie)
- Ø alcohol
Complications> know, prevent, treat
