Cirrhosis Flashcards
What is Laennec’s (Alcoholic) portal cirrhosis?
Scar tissue out #’s normal cells and the liver is unfunctional; results of alcohol or nutritional probs
Postnecrotic cirrhosis is what?
Complication of hepatitis/hepatoxins
What is biliary cirrhosis?
Chronic biliary obstruction/infection and scarring from diseases of the bile duct
What is cardiac cirrhosis?
From long standing right CHF
What is the primary risk factor for cirrhosis?
Alcohol consumption
What are other risk factors?
Malnutrition: low protein intake, high phosphate intake; occupation exposure; men between ages 40-60
What are the early clinical manifestations of?
Liver enlargement/fatty liver, vascular changes, abnormal labs: Tiny increases in ALT/AST/LDH/PT and decreased albumin
How do you get rid of a enlarged/fatty liver?
Quit drinking, exercise and maintain a healthy diet
What are the advanced stages severe complications?
Ascities, GI varices, encephalopathy and portal HTN
Where are the 3 main places ascities can accumulate?
Esophagus, rectum and stomach
What is encephalopathy caused by? And some s/s?
Ammonia; Confusion, mental deterioration, somnalence
What is portal HTN?
Increase pressure of blood flow around the liver
What of the liver cannot be reversed?
Fibrosis (thickening/scarring of CT)
What anti-inflammatory is often used for the pharmacological management of cirrhosis?
Colchicine
What potassium sparing diuretic is used for the pharmacological management of cirrhosis?
Aldactone
What meds can cause liver damage?
Barbiturates, tylenol and sedatives
What other meds can be used for the pharmacological management of cirrhosis?
Vit. K, antacids and H2 receptor blockers