Circulatory system Flashcards

1
Q

Tunica intima

A

INNER
Endothelium (epithelial cells)
Reduce friction

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2
Q

Tunica media

A

MIDDLE
Muscle cells
Alter vessel diameter

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3
Q

Tunica externa

A

OUTER
Connective tissue
Protection and anchor to surrounding tissue

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4
Q

Arteries

A

Carry blood AWAY from the heart

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5
Q

Elastic arteries

A

Conducting vessel

High elastin content

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6
Q

Muscular arteries

A

Distributing vessels
Thick tunica media
Change diameter to control blood flow

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7
Q

Arterioles

A

Resistance vessels
Thin walls, mainly TM
Control resistance to blood flow and flow into capillaries

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8
Q

Capillaires

A

Connect arteries and veins

EXCHANGE VESSELS - site of nutrient exchange

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9
Q

Continuous capillaries

A

Endothelial cells
Gaps in endothelial cells = intercellular clefts
Fluid and sml solutes enter via IC clefts

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10
Q

Fenestrated capillaries

A

Endothelial cells
Pores = fenestrations increase permeability
Larger volumes of fluid and solutes can enter/exit

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11
Q

Sinusoidal capillaries

A

Endothelial cells
Large gaps = sinusoids = leaky
Larges molecules to pass through

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12
Q

Terminal arteriole

A

Supplies capillary bed with O2 blood

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13
Q

Terminal venule

A

Drains deO2 blood from capillary bed

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14
Q

Veins

A

CAPACITANCE VESSLES
Tunica intima forms valves
Thick tunica externa
60% blood volume reservoir in veins

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15
Q

Blood flow

A

The VOLUME of blood flowing through a vessel organ or the entire circulation in a given time period

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16
Q

Blood pressure

A

The FORCE exerted on a vessel wall by the blood in that vessel

17
Q

Resistance

A

Opposition to blood flow

Friction

18
Q

BF =

A

P/R

19
Q

PP =

A

Difference between systolic and diastolic pressure

S - D

20
Q

MAP =

A

D + 1/3(PP)

21
Q

In which vessel does the biggest drop in BP occur

A

Capillaries
High P can damage thin walls
Permeable, so low P required for fluid exchange

22
Q

How do veins provide adequate venous return

A
Valves
Muscle pump
Respiratory pump
Pulsation 
Venoconstriction
23
Q

Functions of autoregulation of BP

A

Metabolic control

Myogenetic (muscle) control

24
Q

Functions of neural regulation of BP

A

Cardioinhibitory: parasymp to SA and AV nodes to dec HR and CO

Cardioacceletory: symp to SA and AV nodes to inc HR and CO AND symp to ventricular myocardium to inc force (SV) and CO

Vasomotor: symp to change vessel diameter **Baroreceptor reflex

25
Q

Functions of renal mechansms

A

Direct mechanism: rate of urine formation

Indirect mechanism: RAAS

26
Q

RAAS

A
Dec Art P
Inhibits baroreceptors
Inc RENIN release. Stimulates:
- Angiotensinogen 
- Angiotensin I (ACE)
- ANGIOTENSIN II:
  1. Stims inc aldosterone release to inc Na+ (and water) reabsorption
  2. Inc ADH release == inc water reabsorption
  3. Inc thirst == inc water intake
  4. Vasocontriction == inc peripheral resistance

==> Inc MAP

27
Q

Baroreceptor reflex for inc BP

A

Barorecs stimulates
Inc parasymp and dec symp to heart = dec HR, SV and CO
Dec symp to tunica media = vasodilation = dec R
=> Dec CO and R == dec BP to homeostatic range

28
Q

Baroreceptor reflex for dec BP

A

Barorecs inhibited
Dec parasymp and inc symp to heart = inc HR, SV and CO
Inc symp to tunica media = vasoconstriction = inc R
=> Inc CO and R == inc BP to homeostatic range

29
Q

Hormones that inc BP

A

A
NA
Angiotensin II

30
Q

Hormones that dec BP

A

Atrial natriuetic peptide (ANP)