Circulatory Disorders Flashcards
Hypertension refers to
persistent high blood pressure that is defined as systolic blood pressure above 140 mm Hg and diastolic blood pressure above 90 mm Hg
hypertension increases
afterload which makes ventricles work harder to expel blood
in hypertension the myocardium
enlarges, stretches excessively and loses efficiency
hypertension is a major cause of stroke
because arteries in brain become more prone to rupture
hypertension is a major cause of kidney failure
because arterioles thicken and renal blood flow decreases
-positive feedback releases angiotensin II and aldosterone, which raise blood pressure to improve blood flow through kidneys
primary hypertension accounts for
90% or all cases, and results from a collection of factors that cannot be attributed to a single cause
obesity increases the
overall length of blood vessels which increases peripheral resistance and raises BP
sedentary lifestyle, diets high in saturate fat and cholesterol, diets low in potassium, magnesium, and calcium contributes to
hypertension
nicotine has devastating effects
on heart by stimulation vasoconstriction and increasing afterload, which makes myocardium work harder
treatments of hypertension include
weight loss, aerobic exercise, dietary changes, and drugs
diuretics help to…
decrease blood pressure by reducing the blood volume
ACE inhibitors help to…
block the formation of angiotensin II, which decreases sodium and water retention so blood pressure goes down and cardiac output goes up
beta-blockers help to…
decrease heart rate and contractility by preventing response to norepinephrine when it binds to adrenergic receptors
calcium channel blockers help to….
inhibit flow of calcium ions into cardiac muscle which reduces cardiac workload
secondary hypertension can be caused by
kidney disease, atherosclerosis, hypersecretion of aldosterone, Cushing disease, and/or polycythemia
coronary atherosclerosis can be triggered by
damage to endothelium of an artery which causes monocytes to adhere to damaged endothelium and penetrate it
monocytes become macrophages and
absorb fats and cholesterol to form fatty streaks on artery wall
platelets adhere to damaged endothelium
and release chemicals that stimulate formation of atherosclerotic plaque
smooth muscle and elastic tissue get replaced by scar tissue
and artery becomes rigid and susceptible to obstruction (arteriosclerosis)
hypertension tends to
run in families
-children whose parents have hypertension are twice as likely to develop hypertension
hypertension is 30% more common in
blacks than whites
hypertension is more common among
men between ages 18 to 54, but more common women older than 65
circulatory shock is where
cardiac output fails to deliver enough oxygen and nutrients to meet our metabolic needs
cardiogenic shock is caused by
inadequate pumping of the heart usually due to MI
hypovolemic shock is characterized by
low blood pressure, weak pulse, and tachycardia following significant blood loss from a sudden hemorrhage or from dehydration
hypovolemic shock effects
trauma, internal bleeding, excessive sweating, diarrhea, or vomiting can eliminate much fluid that water is transferred from blood to tissues
in hypovolemic shock, venous return
declines, stroke volume decreases and cardiac output falls
obstructive shock occurs when
blood flow is block (pulmonary embolism)
vascular shock occurs when
too much blood accumulates in limbs
anaphylactic shock is
a severe allergic response that releases huge amounts of histamines which triggers rapid vasodilation
head trauma can produce
neurogenic shock and sudden loss of vasomotor tone
septic shock occurs when
bacterial toxins trigger vasodilation
transient vascular shock may occur
after prolonged exposure to sun
an aneurysm is
a thin, weakened section in a blood vessel that bulges outward and may eventually rupture, leading to massive hemorrhage
varicose veins are
weak, distended superficial veins with leaking valves in the legs, which causes blood pooling
in varicose veins fluids leak into
surrounding tissues and cause pain and inflammation
edema is
the accumulation of excess fluid in a tissue due to increased capillary filtration and reduced capillary reabsorption
a stroke, or cerebrovascular accident, is
the sudden death of brain tissue due to cerebral ischemia
brief episodes of cerebral ischemia produce
transient ischemia attacks characterized by dizziness, headache, loss of vision, and other sensory losses