Circulation Flashcards
Blood that is drawn directly from an on-site donor and does not undergo processing into separate components (RBCs, plasma, and platelets)
Fresh Whole Blood (FWB)
Oxygen carrying capability of the blood
Red blood cells
Cell fragments that are integral to clot formation
Platelets
Contain ALL of your clotting factors/coagulation factors needed in the process to form fibrin strands which cement the platelet plug for clotting
Plasma
Fresh whole blood contains:
RBCs
Platelets
Plasma
Immunological components (WBCs, antibodies, cytokines)
This is used to prevent the blood from clotting and prevent the cells from lysing during the time from collection to delivery.
CPD solution (anticoagulant Citrate and nutrient Phosphate and Dextrose)
Fresh whole blood has a shelf life of:
24-48 hours
Contain markers on surface that characterize the cell type
Also known as antigens-proteins and sugars that the body use to identify the blood cells that belong to the body
RBCs
Classification determined by presence or absence of antigens
ABO
Meaning it has a Rh factor
Rh positive
Meaning without Rh factor
Rh negative
This blood type has neither A & B markers
Type O
This blood type doesn’t have A or B markers, and it doesn’t have Rh factor.
O negative
This blood type doesn’t have A or B markers but does have Rh factor.
One of the two most common blood types
O positive
This blood type has A marker with no Rh factor
A negative
This blood type has A marker and Rh factor, but not B marker. One of the two most common blood types.
A positive
This blood type has B marker only and no Rh factor
B negative
This blood type has B marker only
B negative
This blood type has B marker and Rh factor, but not A marker.
B positive
All males can receive what type of blood at any time?
O positive and O negative
All females of childbearing age receive what type of blood
O negative
The only oxygen-carrying cell circulating and are needed to halt and repay oxygen debt.
RBCs
30-40% blood loss
1) 1500-2000 ml of blood loss
2) > 120 pulse rate per minute
3) Decreased blood pressure
4) 30-40 respirations per minute
5) Urine output 5-15 ml per hour
6) Level of Consciousness exhibiting confused demeanor
Class III Hemorrhagic shock
> 40% of blood loss
1) > 2000 ml of blood loss
2) > 140 pulse rate per minute
3) Decreased blood pressure
4) > 35 respirations per minute
5) Urine output negligible
6) Level of Consciousness exhibiting lethargic demeanor
* Absent radial pulse/systolic blood pressure below 80mmHg*
Class IV Hemorrhagic shock
Potentially life-threatening reaction caused by acute intravascular hemolysis of transfused red blood cells
Hemolytic reaction
Severe hemolytic reactions can occur with as little as how much blood?
10-30 mL
Presenting signs following a blood transfusion :
1) Fever
2) Chills
3) Flank pain
4) Oozing from intravenous sites
Hemolytic reactions
Treatment for hemolytic reactions
Aggressive hydration and diuresis
Recommendation is to give 1 amp of ________ every 4 units of FWB to avoid toxicity and hypocalcemia
Calcium Gluconate
These are common following a blood transfusions; these reactions are characterized by fever, usually accompanied by chills, in the absence of other systemic symptoms.
Febrile non-Hemolytic Reactions
Most common cause of febrile non-hemolytic transfusion reactions due to:
Release of cytokines from WBCs
Treatment for Febrile non-Hemolytic Reactions
1 gram of Tylenol PO/PR every 8 hours
Any allergic reaction other than _______ constitutes an anaphylactic transfusion reaction
Hives
Treatment for anaphylaxis reaction
IM Epinephrine, antihistamines, vasopressors
Are associated with hives but no other allergic findings
Urticarial Reaction
Immediate actions for hemolytic reactions
Immediately stop
Maintain IV/IO line with fluid bolus
Assess for symptoms
Measure vital signs and perform a physical examination
Confirm the correct product was transfused
Contact your local ______________ to coordinate screening your unit for cross type and match
Armed Services Blood Program (ASBP)
Fill out the back of the TCCC card or an ________ prior to transfusion and record vital signs every 10-15 minutes during transfusion
SF 518