Circovirdae

Question 0

Etiology of post weaning multi systemic wasting syndrome (PMWS)?

Answer 0

porcine circovirus 2

Question 1

What type of inclusion bodies do circoviruses have?

Answer 1

botyroid (grape-like) basophilic IBs

Question 2

T/F: inclusion bodies of circoviridae are only in the nucleus

Answer 2

False!! Ibs are in the cytoplasm OR nucleus Replicates in the nucleus

Question 3

T/F: Parvo and Circoviridae have ssDNA

Answer 3

True :)

Question 4

T/F: Circoviridae has no envelope and is a small spherical virus

Answer 4

True!!

Question 5

Etiology of chicken infectious anemia?

Answer 5

Avian circovirus -contagious to young chicks 2-4 weeks - pale bone marrow and watery blood with low PCV

Question 6

What protein of the avian circovirus induces apoptosis of infected cells?

Answer 6

Apoptin

Question 7

Etiology of Porcine dermatitis & nephropathy syndrome?

Answer 7

Porcine Circovirus 2

Question 8

Gyrovirus is the genus of what circovirus disease?

Answer 8

Chicken infectious anemia **Think of chicken gyros. Nomz.

Question 9

Which type of porcine circovirus is Non-Pathogenic?

Answer 9

Type-1

Question 10

Porcine circovirus Type-2 is also know as what?

Answer 10

(PMWS) Post-Weaning Multisystemic Wasting Syndrome

Question 11

What structural characteristic is indicative of chicken infectious anemia virus?

Answer 11

12 trumpet-like structures

Question 12

Chicken Anemia Virus (CAV) is a member of what genus?

Family?

Answer 12

Genus: Gyrovirus

Family: Circoviridae

Question 13

T/F: Chicken Anemia Virus (CAV) is a highly contagious disease in young chickens.

Answer 13

True: (Usually 2-4 weeks of age)

Older chickens are more resistant to clinical disease.

Question 14

How is Chicken Anemia Virus (CAV) transmitted?

A. Feces and feather dander

B. Horizontal transmission through inhalation or oral exposure

C. Vertically through egg

D. All of the above

Answer 14

D. All of the above

Question 15

What are the three principal replication sites of Chicken Anemia Virus ?

Answer 15

1. Hemocytoblasts in the bone marrow
2. Precursor T cells in the cortex of the thymus
3. Dividing CD4 and CD8 cells in the spleen

Question 16

T/F: Replication in the hemocytoblasts leads to immunosuppression, while replication in the T cells causes anemia.

Answer 16

FALSE:

Replication in the hemocytoblasts leads to anemia, while replication in the T cells causes immunosuppression.

Question 17

What virulence factor causes destruction of infected lymphocytes in the CAV virus?

Answer 17

Apoptin protein which induces apoptosis.

Question 18

CAV can cause blood to be watery and clot slowly as a result of thrombocytopenia because of what factors?

Answer 18

Immunosuppression

and

Aplastic Anemia