Asfarviridae

Question 0

This is the only known DNA arbovirus

Answer 0

African Swine Fever!

Sole member of Family Asfarviridae

Question 1

site of replication/inclusion bodies for Asfarviridae?

Answer 1

Cytoplasm

remember this,

“As far as I know, it replicates and leaves IBs in the cytoplasm”

Question 2

T/F: African Swine Fever is stable as shit

Answer 2

True.

• resistant to wide range of pH (hours @ pH 4 or pH 13)
• survives at least 30 days in pens
• remains viable in blood, feces and tissues (esp meat)

Question 3

T/F: African Swine Fever can replicate readily in any species

Answer 3

FALSE!

Although ASF can be adapted to grow in cells from different species it DOES NOT REPLICATE READILY in any species other than SWINE.

Question 4

Remember this….

Answer 4

ASF does not hemagglutinate.

Hemadsoprtion (HAD) is attributed to a virus specific protein that appears on plasma membrane of infected cells during late infection

Question 5

All of the following are true regarding ASF except:

A. No vaccine
B. Only DNA arbovirus
C. Transmitted by the soft tick Ornithodoros      
D. Reportable
E. Present in North America

Answer 5

E. If it is reportable, you aren’t going to find that shit in North America

Question 6

Transmission of ASF virus between warhogs and soft ticks is known as the __________ cycle

Answer 6

Sylvatic cycle

*Older wild pigs persistently infected, but rarely develop viremia

Question 7

Name some effects of ASF virus

Answer 7

Primarily hemorrhages and apoptosis

Question 8

Are the virions in Asfarviridae enveloped?

Answer 8

Yes