Cinetica gastrointestinal Flashcards

1
Q

Metabolismo CYP?

A

IBP (3A4,2C19)
Domperidona (3A4)
Ondasetrón (1A2,2D6,3A4)
Aprepitant (3A4)
Loperamida (3A4)

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2
Q

Ajuste IR?

A

IBP
Ondasetrón

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3
Q

Ajuste IH?

A

Antag. H1
Aprepitant

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4
Q

Metabolismo x esterasas?

A

Bisacodilo

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5
Q

Metabolismo x conjugación?

A

Metoclopramida

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6
Q

Metabolismo x bacterias?

A

Picosulfato sodio
Lactulosa

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7
Q

Adm oral?

A

TODAS (excepto fosaprepitant - EV)
-de los anti H1 solo la famotidina

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8
Q

Adm EV?

A

IBP (solo para HDA)
Ant H1
Ondasetrón
Aprepitant
Metoclopramida

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9
Q

Adm IM?

A

Metoclopramida
Ondasetrón

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10
Q

Sustrato e inhibidor de CYP?

A

Aprepitant

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