Churg Strauss

Question 1

What is Churg Strauss?

Answer 1

eosinophilic granulomatous with polyangiitis is a systemic autoimmune small vessel vasculitis

Question 2

What is Churg Stauss usually accompanied by?

Answer 2

asthma and eosinophilia

Question 3

What antibodies are usually present in Churg Strauss?

Answer 3

p-ANCA antibodies

Question 4

What is the presentation of Churg strauss?

Answer 4

1. History of asthma, allergic rhinitis or sinusitis
2. Skin nodules, palpable purpura
3. Peripheral neuropathy
4. Can involve heart, GI tract and kidneys (pauci-immune complexes)

Question 5

What investigations and results are present in Churg Strauss?

Answer 5

1. ESR/CRP- elevated
2. p-ANCA- positive
3. Serum IgE- elevated levels

Question 6

What is the management for Churg strauss?

Answer 6

1. Oral steroids (prednisolone) needed for induction of remission and maintenance
2. Steroid sparing agents if not tolerated

Question 7

What are possible complications of churg strauss?

Answer 7

Corticosteroid side effects

Question 8

What are possible DDx for Churg Strauss?

Answer 8

1. Wegdner’s

2. MPA