chronic lymphocytic leukaemia Flashcards
1
Q
what is chronic lymphocytic leukaemia?
A
- excess production and accumulation of B lymphocytes
2. build up in bone marrow, lymph nodes and blood
2
Q
disease progression of CLL?
A
very slow growing cancer
3
Q
How does CLL present?
A
assymptomatic mainly
4
Q
Clinical features of CLL?
A
- painless lymphadenopathy
- hepatosplenomegaly
- fever
- night sweats
- weight loss
5
Q
How is CLL diagnosed?
A
- blood tests - lymphocytosis
2. peripheral blood smear - smudge cells
6
Q
Mx
A
Chemotherapy/Radiation
7
Q
at what age does it present?
A
> 60 years