chpt 8 physical and chemical injuries Flashcards
Common alteration of the buccal mucosa most often associated with pressure, frictional irritation, or sucking trauma from the facial surface of teeth, 13% of population
linea alba
What is the clinical presentation of linea alba
white line, bilateral at level of occlusal plane with no other associated problems
Linea alba treatment
None, no biopsy
What causes linea alba
hyperkeratosis
Lesion from chronic, habitual nibbling with a higher incidence in females presenting with thickend, shredded, white areas
Morsicatio Bucarum
How would differentiat Morsicatio Buccarum from Luekoplakia from Lichen planus
Morsicatio bucarum has ragged torn look Leukoplakia has homogenous look Lichen Planus has Striae of Wickam
What is chronic Lip chewing
Morsicatio Labiorum
Chronic tongue chewing
Morsicatio Linguarum
How could you differentiate Morsicatio Linguarum from Oral Hairy Leukoplakia
biopsy does not show EBV, candidiasis and no history of HIV
Ways to get Ulcerations
1) Physical Thermal
2) Electrical
3) TUGSE
4) Riga-Fede disease
What is TUGSE
Traumatic Ulcerative Granuloma with Stromal Eosinophilia
With what is TUGSE associated
Eosinophils = allergies or parasites
What is the only clinical differentiation between a TUGSE ulcer and an aphthous ulcer
TUGSE is slower to heal (>7 days)
These are traumatic ulcerations of the ventral tongue in nursing babies and are a variation of TUGSE
Riga-Fede disease
Represent 5% of all burn admissions
Electrical burns
2 types of electrical burns and which is most common oral
Contact and Arc. Arc is most common orally with saliva acting as conductor
Age and most common location for electric burns
<4 years old. Lips and commissures presenting charred yellow with little bleeding
3 stages of treatment of ulcers (in order)
1.) Remove obvious injury
2.) Treat symptoms: cellulose films, topical
antibiotics, Orabase)
3.) If not healed in 2 weeks, Biopsy
Are natal teeth associated with Riga-Fede disease extra teeth or are they the babies deciduous teeth simply erupted early
early erupted deciduous teeth.
Sources of Chemical injuries
Aspirin OTC meds
Gasoline
Iatrogenic dental chemicals (formocreosol, etch,
Hydrogen peroxide, Silver nitrate)
Why are OTC meds a source of chemical injuries
Have a lot of eugenol and phenol
How can one get a cotton roll burn
either cotton roll wicks out moisture and causes necrosis, or holds caustic chemicals against the epithelium, or is removed and takes epithelium w/ it
All systemic anticancer therapies (antineoplastic therapies) cause what
death of some normal cells
What are the 2 acute oral changes associated w/ cancer chemotherapy
Mucocitis
Hemorrhage
Where does oral mucocitis associated with cancer chemotherapy present
nonkeratinized surfaces (Buccal mucosa, ventrolateral tongue, soft palate, floor of mouth)
How does Oral Mucocitis associated with cancer chemotherapy and radiation treatment look clinically
early develops white discoloration from lack of keratin desquamation followed by loss of that layer & replacement by atrophic mucosa that is edematous, erythmatous & friable. Finally is ulcerated and covered by yellowish fibrinopurulent membrane
Where does Radition therapy acute mucocitis present
mucosal surface w/in direct portals of radiation
What are the 2 acute changes associated with cancer radiation therapy
Acute mucocitis
Dermatitis
What is the character of Radiation Therapy Dermatitis based on
Varies w/ amount received. Can be erythema, edema, burning, purities all the way to necrosis and deep ulcerations
What are the 5 Sequelae (a pathological condition resulting from disease [Wiki definition]) to Cancer Chemotherapy
- increased susceptibility to infection
- Oral mucocitis
- Oral ulceration
- Increased risk of hemorrhage
- Impaired healing
The introral hemorrhage that is a sequelae of cancer chemotherapy is secondary to what
thrombocytopenia caused by bone marrow suppression
This is a complication associated with head and neck radiation
Xerostomia
What is the course of radiation induced Xerostomia
changes after 1 week. Decrease in saliva after 6 weeks. Parotids dramatically/irreversibly affected. Decreased bactericidal activity of saliva cause increased caries
8 Sequelae of Radiation therapy
1) Hemorrhage 2) Mucocitis 3)Dermatitis
4) Xerostomia 5) Osteoradionecrosis
6) Loss of taste/ altered taste(Hypgeusia/dysguesia) 7) Trismus
8) Developmental anomalies (e.g. microdonts, hyloglossia) –> dependent on age and treatment
What can cause the osteoradionecrosis
hypoxia, hypovascularity, hypocellularity
What increases the risk of developing osteoradionecrosis and what are the treatment limits
Surgery. Do anything you can either 21 days prior to radiation (to allow healing prior to therapy) or wait 1 year after radiation therapy is complete