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Oral Pathology, Stephen > ch 09 allergies and immunologic diseases > Flashcards

ch 09 allergies and immunologic diseases Flashcards

1
Q

Elevated painful fungivform papillae often red, white or yellow in color with unknown etiology resolving on their own

A

Transient Lingual papillitis

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2
Q

This is a common oral mucosal pathoses that is caused by different things in different people, characterized by a large ulcer on nonkeratinized mucosa

A

Aphthous ulcer/Aphthous stomatitis/recurrent aphthous ulcer (RAU)

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3
Q

Layman’s term for Recurrent Aphthous ulcer(RAU)

A

Canker sore

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4
Q

7 factors that can contribute to Recurrent Aphthous Ulcer (RAU)

A

Allergies Genetics
Nutritional deficiency Hematologic abnormalities Hormones
Trauma
Stress

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5
Q

9 systemic disorders associated with Recurrent Aphthous Ulcer (RAU)

A

Bechet’s Syndrome (ocular/orogenital lesions)
Celiac disease (Gluten sensitivity in Small intestine) Cyclic neutropenia (cyclic low neutrophils ~21 days) Nutritional deficiencies
IgA deficiency
Immunocompromised
Inflammatory Bowel Disease
Reiter’s Syndrome (inflammatory arthritis,
conjunctivitis, urethritis/cervicitis)
Sweet’s syndrome (febrile neutrophilic dermatosis)

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6
Q

3 Clinical variations of aphthous ulcer

A

Minor 80% Major 10%

Herpetiform 10%

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7
Q

Aphthous ulcer variation with fewest recurrences, shortest duration, 1-5 lesions buccal and labial mucosa, but very painful

A

Minor aphthous

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8
Q

Longest duration aphthous ulcer taking 2-6 weeks to heat, 1-10 lesions, labial mucosa, soft palate, tonsillar fauces, may cause scaring

A

Major Aphthous

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9
Q

Aphthous ulcer with the most frequent recurrence, greatest number of lesion, up to 100

A

Herpetiform Aphthous ulcers

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10
Q

If see HerpetiformAphthous ulcer, what should be done with medical history

A

)review med history to rule out underlying systemic disorder

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11
Q

2 drugs to treat Herpetiform Aphthous ulcer

A

topical corticosteroids

Injections of triamcinolone acetonide

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12
Q

Treatment for all 3 Aphthous type ulcers

A

steroids

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13
Q

multisystem disorder with oral, genital, ocular lesions, always having oral lesions at some point, looking like aphthous ulcers

A

Behcet’s syndrome

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14
Q

What is required to diagnose Bechet’s Syndrome

A

Recurrent oral ulcers w/ twof of the following: Recurrent genital ulcers
Eye lesions
Skin lesions Positive pathergy

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15
Q

What is positive pathergy associated with Bechet’s Syndrome

A

skin reaction to the injection of sterile saline

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16
Q

Where do aphthous ulcers associated with Behcet’s Syndrome appear orally

A

soft palate and oropharynz

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17
Q

Treatment for Bechet’s Syndrome aphthous ulcers

A

topical or intralesional corticosteroids or oral colchicines or dapsone

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18
Q

Multisystem granulomatous disorder of unknown etiology

A

Sarcoidosis

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19
Q

What race is more affected by Sarcoidosis

A

Blacks, 10-17 times more than whites

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20
Q

2 age range peaks for Sarcoidosis

A

25-35, 45-65

21
Q

What system is always involved in Sarcoidosis

A

Lymph

22
Q

Sarcoidosis lesions that appear frequently on the nose, ear, lips, and face that are chronic, violaceous (violet color)), indurated

A

Lupus pernio

23
Q

Sarcoidosis lesions that are scattered, nonspecific tender erythematous nodules, frequently occurring on the lower legs

A

Erythema nodosum

24
Q

What causes Sarcoid lesions

A

noncaseating granulomas

25
Q

2 syndromes associated with Sarcoidosis

A

Lofgren’s syndrome Heerfordt’s syndrome

26
Q

Character of Lofgren’s Syndrome

A 
Erythema nodosum (sarcoid)
Bilateral hilar lymphadenopathy (sarcoid) Arthralgia (joint pain)
27
Q

Character of Heerfordt’s Syndrome (good board question)

A

uveo-parotid fever
Parotid enlargement
Anterior uveitis (eye inflammation) Facial paralysis
Fever

28
Q

This is a trashcan disorder that is diagnosed by the exclusion of other disorders. It’s character is nonspecific granulomatous inflammation

A

Orofacial granulomatosis

29
Q

What 4 other granuloma diseases must be ruled out before diagnosing Orofacial Granulomatosis

A

Sarcoidosis
Chrohn’s disease (form of irritable disease)
Fungus infection Foreign body reaction

30
Q

Orofacial granulomatosis + Facial paralysis + fissured tongue (board question)

A

Melkersson-Rosenthal Syndrome

31
Q

Allergic reaction of the oral mucosa to the systemic administration of a medication

A

stomatitis medicamentosa

32
Q

2 best things to do when person comes in with highly ulcerated mouth

A

list of meds, when they started taking each one, and how long the ulcers have been there

33
Q

Allergic contact stomatitis caused by what and is prevalent in which gender

A

diverse topical agents Female predilection

34
Q

Acute Allergic Contact stomatitis symptoms

A

burning Redness
Edema
Itching, stinging, tingling

35
Q

Chronic Allergic Contact stomatitis symptoms

A

erythematous White/hyperkeratotic Erosions in affected zone

36
Q

4 ways to treat Allergic Contact stomatitis

A

remove suspected allergen Antihistamine therapy
Topical anesthetic (dyclonine HCl)
Topical corticosteroids (fluocinonide gel or
dexamethasone elixir)

37
Q

Unique inflammatory skin disease that involves the circumoral area

A

Perioral dermatitis

38
Q

What exacerbates perioral dermatitis

A

Topical corticosteroid application

39
Q

Treatment of perioral dermatitis

A

Metronidazole

40
Q

What is a risk of cinnamon flavoring

A

Contact stomatitis on gingiva

41
Q

What does cinnamon flavor induced contact stomatitis resemble

A

plasma cell gingivitis (irradescent red gingivitis)

42
Q

When there is a hypersensitivity to a dental metal, what metal is it

A

Mercury

43
Q

Lichenoid lesion only in the area of a dental material

A

Lichenoid contact stomatitis

44
Q

Hypersensitivity reactions to dental metals disappear after how many days once metal is removed

A

10-14 days

45
Q

Most commonly affected sites for Lichenoid contact stomatitis

A

posterior buccal mucosa, ventral surface of lateral border of the tongue

46
Q

46.)Diffuse edematous swelling of the soft tissues that most commonly involves the subcutaneous and submucosal connective tissues but may affect the GI or respiratory tract , occasionally fatal

A

Angioedema/Quincke’s disease

47
Q

Most common cause of Angioedema

A

Mast cell degranulation causing histamine release

48
Q

2 ways to treat angioedema

A

PO antihistamine IM Epinephrine

Oral Pathology, Stephen (13 decks)

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