CHP 4

Question 1

Allelic Series

Answer 1

Describes the dominance hierarchy of multiple alleles

Question 2

Some alleles are dominant because

Answer 2

The wild type alleles produce a functional polypeptide

Question 3

Types of mutant alleles

Answer 3

Recessive amorphic(loss of function) - nonfunctional polypeptide
Recessive hypomorphic(loss of function) - nonfunctional polypeptide
Dominant negative allele - produces polypeptide that interferes with the wild-type polypeptide peptide

Question 4

Penetrance

Answer 4

Describes how the mutant allele is incomplete and doesn’t always express itself

Question 5

Expressivity

Answer 5

Dominant mutant allele influences phenotype to different degrees

Question 6

complementary epistasis

Answer 6

2 genes need a dominant allele to produce a phenotype

9:7

Question 7

recessive epistasis

Answer 7

Homozygous recessive of one gene masks both alleles of another gene
9:3:4

Question 8

Dominant epistasis 1

Answer 8

Dominant allele of one gene hides effects of both alleles of another gene

Question 9

Dominant epistasis 2

Answer 9

Dominant allele of one gene hides effects of a dominant allele of another gene

Question 10

Pleiotropy

Answer 10

When one gene has more than one phenotypic effect

Question 11

Inbreeding coefficient

Answer 11

The probability that the two gene copies in an individual are identical by descent from a common ancestor