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Pharm Test II > Cholinergic drugs > Flashcards

Cholinergic drugs Flashcards

1
Q

Nicotine type and Rx

A

type: nicotinic agonist (Nn)
Rx: smoking cessation

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2
Q

Succinylcholine type and Rx

A

Nicotinic receptor agonist

rx: muscle relaxant during endotracheal intubation (Nm)

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3
Q

Methacholine type and Rx

A

direct acting muscarinic agonist (quat N)

Rx: diagnosis of asthma

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4
Q

Methacholine tox and contrainidcation

A

toxicity: Bronchiole constriction
contraindication: b blockade

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5
Q

Carbachol type and Rx

A

type: direct acting muscarinic agonist (quat N)
Rx: miotic agent for ocular surgery/ glaucoma

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6
Q

Carbachol toxicity

A

excessive muscarinic activation (bronchoconstriction, reduced cardiac conduction)

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7
Q

Bethanechol type and Rx

A

type: direct acting muscarinic agonist (quat N)
Rx: post op urinary retention and neuro bladder atony

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8
Q

Bethanechol Tox and Contraindications

A

tox: bradycardia, bronchoconstriction
Contraindications: asthma, peptic ulcer, bradycardia

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9
Q

Pilocarpine Type and Rx

A

Direct actin muscarinic agonist

Rx: dry mouth and neck (radiotherapy or Sjorgens, open and closed angle glaucoma

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10
Q

Pilocarpine tox

A

Excess muscarinic activation (slow Av cond), hypotension, excessive salivation, bronchoconstriction

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11
Q

Neostigmine type and Rx

A

reversible AchE inhibitor (Nm)

rx: myasthenia gravis

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12
Q

Neostigmine tox and contraindications

A

muscarinic/ nicotinic excess

contrainindication: intestinal obstructions

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13
Q

Edrophonium type and Rx

A

type: reversible AchE inhibitor (Nm)
Rx: myasthenia gravis

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14
Q

Edrophonium Tox and contraindications

A

tox: bradycardia/ standstill
contraindications: intestinal/ urinary blockade

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15
Q

Physostigmine type and Rx

A

reversible AchE inhibitor (crosses BBB)

Rx: antidote for muscarinic antagonist poisoning

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16
Q

Physostigmine tox and contraindications

A

tox: convulsions, respiratory, and CV depression
contraindications: asthma, CV disease, intestinal obstruction

17
Q

Donepezil type and Rx

A

reversible AchE inhibitor

Rx: Alzheimers (just inhibits AchE)

18
Q

Echothiphate type and Rx

A

irreversible AchE inhibitor

Rx: long term miosis for open angle glaucoma

19
Q

Atropine type and Rx

A

Competitive muscarinic antagonist
Rx: organophosphate poisoning, mydriasis and cycloplegia, reverse bradycardia of vagal origin, reverse gastrointestinal hypermotility, bladder spasms

20
Q

Scopolamine type and Rx

A

competitive muscarinic antagonist

Rx: nausea and vomiting from motion or chemo

21
Q

Scopolamine Tox

A

anti-muscarinic actions

22
Q

Glycopyrrolate type and Rx

A

competive muscarinic angagonist

Rx: protect against excessive muscarinic effects of AchE inhibitros durin neuromuscular blockade

23
Q

Glycopyyrolate Tox

A

heat stroke (no sweating)

Pharm Test II (7 decks)

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