Cholinergic Agents and Blockers Flashcards
1
Q
tubocurarine
A
postsynaptic site of action
2
Q
tubocurarine
A
neuromuscular blocker non depolarizing
3
Q
decamethonium
A
used in surgery to lower BP
4
Q
hexamethonium
A
nicotine-prolonged depolarizaiton
5
Q
blocks choline uptake
A
hemicholinium
6
Q
false NT
A
triethylcholine (synthesis of NT)
7
Q
block transport of choline
A
hemicholinium, triethylcholine
8
Q
vesamicol
A
storage (block transport into vesicles)
9
Q
hexamethonium
A
ganglion blocker (not used clinically)
10
Q
ganglion blocking drugs
A
interfere with acetylcholine release
11
Q
ganglion blocking drugs
A
botulinum toxin, hemicholinium, Mg2+
12
Q
depolarizing drugs
A
succinylcholine, acetylcholine
13
Q
depolarizing drugs
A
two phases: depolarization and desensitization
14
Q
non-depolarizing drugs
A
tubocurarine, vecuronium
15
Q
mechanisms of GBD
A
- interference with Ach release
- nicotine-prolonged depolarization
- interfere with postsynaptic Ach action
- block nicotinic receptors
- block autonomic and enteric ganglia
