Cholinergic agents

Question 1

M cholinoreceptor agonists

Answer 1

Pilocarpine

Question 2

Anticholinesterases/Carbamates/Carbamine acid esters

Answer 2

Neostigmine
Piridostigmine

Question 3

Anticholinesterases/ Organophosphorus compounds/Phosphoric acid esters

Answer 3

Insecticides:
Methyl parathion
Parathion

Nerve gases:
Sarin
Somane
Tabune

Question 4

Toxicology of cholinesterase inhibitors

Answer 4

D diarrhea, defecation U urination
M miosis
B bronchoconstriction B bradycardia
E excitation (of skeletal muscle and CNS) L lacrimation
S salivation
S sweating

Question 5

Antidotes of cholinesterase inhibitors

Answer 5

Atropine
Pralidoxime

Question 6

M cholinoreceptor antagonists

Answer 6

Atropine

Question 7

Antimuscarinic toxicity

Answer 7

Central:
Sedation/Coma
Delirium with visual hallucinations Seizures

Peripheral:
Dry mucous membranes
Dry warm skin
Tachycardia
Mydriasis
Hyperthermia
Ileus
Urinary retention

Question 8

Antidotes of Antimuscarinic toxicity

Answer 8

Physostigmine
Neostigmine

Question 9

N cholinoreceptor agonists

Answer 9

Nicotine
Suxamethonium sin. succinylcholine

Question 10

Local ACh release inhibitors

Answer 10

Botulinum toxin type A

Question 11

Antidote of N cholinoreceptor antagonist

Answer 11

Sugammadex

Question 12

N cholinoreceptor antagonists

Answer 12

Tubocurarine
Rocuronium