Chimiotherapie Flashcards

1
Q

Toxicité vincristine ? (2)
(alcaloïde extrait pervenche Madagascar)

= inh polymérisation microtubules, arrêt mitose

A

Neuropathie périphérique

Constipation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Toxicité antracycline (-rubicine) ? (2)

= intercalant (paire azoté ADN), inh topo II

A

Toxicité cutanée si extravasation

Toxicité cardiaque

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Toxicité aracytine? (3)

= anti métabolite

A

Fièvre
Toxicité cutanée
Toxicité cérébelleuse

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Toxicité cyclophosphamide ? (2)

= agent alkylant

A

Cystite hémorragique

Cancer vessie

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Toxicité asparaginase? (3)

= cytostatique (rend impossible blaste sur produire propre asparagine)

A

Toxicité hépatique
Pancréatite
Risque de thrombophlébite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Toxicité methotrexate ? (3)

= anti métabolite, inh dihydrofolate reductase

A

Fibrose hépatique
Fibrose pulmonaire
Nephrotoxique

How well did you know this?
1
Not at all
2
3
4
5
Perfectly