Child Health Disease Profiles Flashcards
what is term baby
birth between 37 and 42 weeks
what is normal weight for baby
2.5-4kg
how much weight should babies gain during the 3rd trimester
24g per day
when does trans placental transfer occur
3rd trimester
what are transferred in trans placental transfer
iron, vitamin, calcium, phosphate and antibodies
during contraction the baby is in what environment
hypoxic
what does prolonged labour reduce
fetal reserves
how can things like maternal smoking or drug use of mother affect babies for when giving birth
placenta insufficiency so difficult for Abby to cope with hypoxia
stress baby eperiences during labour increases what
adrenaline and cortisol
what does first cry/ breath cause
alveolar expansion
what is a score to measure perinatal adoption
Apgar
when is there decreased pulmonary arterial pressure and increased Pao2
perinatal adaptation
what is the calorific intake in the first 24hrs of baby
little intake
are babies alert immediately after delivery
very
what is given to newborn babies to prevent haemorrhage disease (disorder of clotting)
Vitamin K (prefer intramuscular)
if what is present in infection screen you should give vaccination for immediately
Hep B
Hep B and C, HIV, Syphillis, TB, Group B strep are screened in what
infection screen
what is an anticipatory method used to monitor babies at risk
early warning systems
mothers should have what vaccine
pertussis and influenza
what are some things you want to screen for in newborn
cystic fibrosis, hypothyroid and haemoglobiopathies
things that increase risk of giving birth early
- already had greater than 2 preterm babies
- abnormally shaped uterus
-multiple pregnancy
interval of less than 6 months between pregnancy
-IVF
smoking, alcohol, drugs - poor nutrition, some chronic conditions eg high BP or diabetes, multiple miscarriages or abortions
what babies need more help to stay warm
preterm babies
altered approach to preterm babies
delay cord clamping if possible, keep baby warm, gentle lung inflation(PEEP) and oxygen sat monitor
what does high surface area to body mass of baby result in
more likely to lose heat
babies BMR is what in hypothermia
low
what occurs usually 6-8 weeks after delivery
retinopathy of prematurity
what is early metabolic complication of prematurity
hypoglycaemia and hyponatrermia
what is late metabolic complications of preterm
osteopenia
do you want apgar score to be high or low
high
what is fluid in the lungs that does no clear in newborns
Transient tachypnoea of the newborn
2 examples of congenital respiratory disease of the newborn
tracheo-oesophageal fistula and diaphragmatic hernia
examples of a rhesus disease
hydrops foetalis
some congenital heart disease
tetralogy of allot, transposition of great arteries, coarction of the aorta
what are these; hypoxic ishcaemic encephalopathy, microcephaly, spina bifida
neurological illnesses of the newborn
renal illness of newborn
potters syndrome
muscular illness of newborn
myotonic dystrophy
problems related to glucose of newborn
hypoglycaemia
error of metabolism in newborns can cause
acidosis
potenital management of circulation of newborns
fluids, inotropes
early onset neonatal sepsis is acquired when
before and during delivery
early onset neonatal sepsis type of bacteria
Group B strep
late onset neonatal sepsis organism
coagulase negative staph or staph aureus
symptoms of neonatal sepsis
fever
reduced tone and activity
poor feeding
vomiting
signs of neonatal sepsis
respiratory distress or apnoea
tachycardia or bradycardia
hypoxia
jaundice within 24hrs
when might be a baby be hypoglycaemia
neonatal sepsis
does jaundice occur in most normal term babies and ore term babies
yes
jaundice is caused by hyperbilirubinaemia that is
unconjugated
what hyperbilirubinaemia is always pathological
conjugated
is unconjugated hyperbilirubinaemia always pathological
no can be physiological or pathological
reasons for physiological jaundice
increased RBC breakdown or immature liver
main reason for physiological jaundice in premature babies
immature liver
how long does breast milk jaundice take to resolve
1.5-4 months
what is a common cause of jaundice in the first 24 hours of life
neonatal sepsis
what could be as a result of high levels of conjugated bilirubin
biliary atresia, Total parental nutrition, hypothyroidism, cystic fibrosis, trisomy 21
what is prolonged jaundice in a term baby and in a pre term baby
over 14 days in a term baby or 21 days in a preterm
is jaundice in the first 24hrs of life physiological or pathological
PATHOLOGICAL
what test to do if got early jaundice
FBC, serum bilirubin level and DCT (Coombs test)
tests done for prolonged jaundice
FBC< serum bilirubin level, liver function tests and thyroid function tests
treatment for early jaundice
phototherapy, hydration and underlying cause
what affects 75% of infants born before 29 weeks
respiratory distress syndrome
medical term for lung collapse
atelectasis
how does respiratory distress affect co2 levels
hypercapnia
respiratory distress affects what in lungs
alveoli
signs of respiratory distress
tachypnoea, grunting, intercostal recession (undraping between the ribs), nasal flaring, cyanosis
when should respiratory distress then gradually improve
2-4 days
management of respiratory distress
maternal steroid and surfactant replacement and ventilation
what can cause respiratory distress
acidosis and hypoglycaemia
what refers to the withdrawal symptoms that happens in neonates of mothers that used substance in pregnancy
neonatal abstinence syndrome
substances that can cause neonatal abstinence syndrome
opiates, methadone, cocaine, cannabis, alcohol
CNS symptoms of neonatal abstinence syndrome
irritability, tremors and seizures
baby could be — in neonatal abstinence syndrome
sweating
babies with neonatal abstinence syndrome kept in hospital for how long
least 3 days
how could a neonate with neonatal abstinence syndrome be supported
quiet and gentle dim environment with gentle handling and comforting
neonatal hypoglycaemia is defined as
blood glucose levels below 2.6mmol/L
3 signs of neonatal hypoglycaemia
lethargy, jitteriness and seizure activity
what helps prevent hypoglycaemia in neonate
early feed and keeping baby warm
how warm should keep neonate
36.6-37.2
in hypoglycaemia baby would rather enterally feed than
feed baby with IV glucose
what do do if neonate is recurrently hypoglycaemic
hypoglycaemia screen
what occurs when a baby doesn’t receive enough oxygen before, during or just after birth
birth asphyxia
causes of brith asphyxia
maternal shock, intrapartum haemorrhage, prolapsed chord or nuchal cord
what is nuchal chord
cor dis wrapped around the neck of the baby
complication of birth asphyxia
hypoxic ischaemic encephalopathy
what is hypoxic ischaemic encephalopathy
multi organ damage due to tissue hypoxia
babies with what can benefit from therapeutic hypothermia
hypoxic ischaemic encephalopathy
what does therapeutic hypothermia do to babies with HIE
reduce risk of cerebral palsy, developmental delay, learning disability, blindness and death
what is floppy baby
neonatal hypotonia
baby with low muscle tone is
neonatal hypotonia
floppy baby has what features
lack of head control, increased range of movement, frog legged, feels like they ll fall out of your grasp
what investigations for neonatal hypotonia
Bloods, neurology review and imaging
central neonatal hypotonia has
normal strength
anterior horn neonatal hypotonia has
generalised weakness
neuromuscular neonatal hypotonia has
weakness in face, eyes an bulbar
muscle neonatal hypotonia has
weakness is proximal more than distal eg face
nerve neonatal hypotonia
weakness id greater distally than proximally
what imaging for neonatal hypotonia
cranial US and MRI
would you use next generation sequencing or acqh for blood for neonatal hypotonia
NGS
what interventions for neonatal hypotonia
resp and feeding support, physio,
treatment for spinal muscular atrophy
RNA targeted therapy
difference between neuromuscular and muscle neonatal hypotonia
neuromuscular has normal DTRs and muscle has decreased DTRs
difference between neuromuscular and muscle neonatal hypotonia
neuromuscular has normal DTRs and muscle has decreased DTRs
what neonatal hypotonia is often describes as alert
anterior horn cell
what is a hydrocephalus
cerebrospinal fluid building up abnormally within the brain and spinal chord
enlarged and rapidly increasing head circumference and bulging anterior fontanelle
hydrocephalus
management of hydrocephalus
ventriculoperitoneal shunt
part of the bowel becomes necrotic in neonates
necrotising enterocolitis
what can cause necrotising enterocolitis
premature baby being fed too early
necrotising enterocolitis symptoms
vomiting green bile, intolerance to feeds, distended tender abdomen with absent bowel sounds and blood in stools
gas in peritoneal cavity in necrotising enterocolitis indicates what
perforation
what does the abdominal X-ray in neonate with necrotising enterocolitis show
dilated bowel, bowel wall oedema and gas in bowel
management of necrotising enterocolitis
nil by mouth and clindamycin and cefotaxime
in neonates when bleeding into the ventricles inside the brain
intraventricular haemorrhage
what is the most common type of intraventricular haemorrhage
germinal matrix
condition that is obliteration of the lumen of the jejunum
jejunal atresia
how does jejunal atresia present
abdominal distenson and bilious ( yellow-greenish) vomitting within the first 24 hrs of birth
how does jejunal atresia present
abdominal distenson and bilious ( yellow-greenish) vomitting within the first 24 hrs of birth
treating jejunal atresia
surgery
malrotation presents with – vomit
green
investigation for malrotation is
upper gi contrast and followthrough
treatment of malrotation is
surgery
what is usually a manifestation of cystic fibrosis
meconium ileus
what is meconium ileus
abnormally thick meconium causing obstruction to the distal ileum
what is caused by a weakness in muscle around the groin
inguinal hernia
cerebral palsy can be from prenatal to less than— post natally
1month
post natal causes of cerebral palsy
meningitis, severe neonatal jaundice and head injury
genetic disease that causes muscles weakness and wasting
duchennes muscular dystrophy
aetiology for duchennes
defect gene for dystrophin on the X chromosome - X linked recessive
how can girls affect duchennes
they can be carriers