Chest wall, mammary glands, and lungs Flashcards
What type of glands are mammary glands?
apocrine; modified sweat glands
What portion of the breast extends into the anterior axillary fold?
tail of Spence
What type of glands are found in the areola?
Montgomery glands (oily sebacesous glands)
What is breast tissue dependent upon?
estrogen; if post menopausal, can’t keep up gland structure
What is the purpose of montgomery glands?
aid in prevention of skin breakdown during lactiation
Where is arterial blood supply to the breast from?
internal thoracic
Venous drainage from the breast is through what vein?
axillary vein
Lymph drainage from breast
primarily axillary, but also lymph nodes in the chest cavity
What innervates the breast?
cutaneous branches of intercostal nerves from T2 to T6.
Suspensory (Cooper’s) ligaments
support ligaments that attach from deep fascia of pec to the dermis; contain lobes and lobules between them
What happens to the duct system with pregnancy?
it expands under hormones; prolactin causes milk production and oxytocin causes milk let down
What is the blood supply to the breast
mainly from internal thoracic a. - it gives off anterior perforating cutaneous arteries (some from lateral thoracic)
Where do the lateral perforating cutaneous arteries that supply the breast stem from?
intercostal arteries - supply it laterally
Where is most of the lymphatic drainage from the breast occur?
75% to axillary nodes
Sentinel node
where the cancer/tumor first drains - if cancer is present, it means it has metastasized
What area of the breast has the highest incidence of cancer?
tail of spence; 60%
Why is mammogaphy limited in younger women?
denser breast tissue
How do you perform a breast exam?
start at nipple and palpate radially making sure to evaluate the tail of spence and axilla, lastly squeeze the nipple to check for discharge
What would the presence of blood discharge from nipple indicate?
breast cancer until proven otherwise
galactorrhea
milk discharge in absence of lactation or pregnancy; causes: excess prolactin production, pituitary adenoma/prolactinoma (would also have headache/visual defect)(bilateral), medications (SSRIs) bilateral.
What are some changes associated with intraglandular problems and possible malignancy?
nipple inversion, dimpling of skin, epidermal edema, lumphedema, peau d’orange
What is the most common benign mammary gland disease?
fibrocystic change
fibrocystic change
hormonal fluctiations in cycle produce proliferation in CT and cysts. Causes mastalgia, lumpiness/pain. Occurs 20-50 yo - not post-menopausal
What is the tx for fibrocystic change?
topical NSAIDs or BC. not good to use hormones and tamoxifen.