Chest Pain And Coronary Syndromes Flashcards

1
Q

What things can we do to try and reach a diagnosis?

A
  • History
  • Clinical examination
  • Investigations
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2
Q

What investigations found be done on a patient with chest pain?

A

ECG

Blood tests - Troponin, something else (full blood count - infections)

Chest X-rays

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3
Q

What is SQUITARS?

A

SQITARS is the criteria we used to assess pain.

Site - location of the pain and if it radiates

Quality - How pain feels (sharp, dull)

Intensity - effect on patient, severity score

Timing - when it started, sudden or gradual onset

Aggravating factors - what makes pain worse

Relieving factors - what makes pain better

Secondary symptoms - other symptoms.

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4
Q

What are some cardiac causes of chest pain?

A
  • Myocardial Infarction
  • Myocardial Ischaemia - angina
    • Both these can present with a dull, central chest pain, both affect the blood supply and both radiate to the shoulder, the neck and the jaw.
  • Pericarditis
  • Aortic Dissection - Pain presents more in the back as a sharp, tearing pain,
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5
Q

Wear are some respiratory causes of chest pain?

A
  • Pneumonia - sharp, worse when breathing
  • Pleurisy - often seen with pneumonia
  • Pericarditis - pericardial sac is inflammed. Breathing in makes it worse
  • Pneumothorax - lung collapse, hear breathlessness and chest X-ray. Predisposed if you have an underlying lung problem such as COPD.
  • Pulmonary Embolism - occurs from a DVT, breathless, sharp and localised pain, acute onset of pain
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6
Q

What are some MSK causes of chest pain?

A
  • Fractured ribs - localised inflammation / pain
  • Costochondrits - localised and tender, inflammation of the costal margins.
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7
Q

What are some upper GI causes of chest pain

A
  • Reflux
  • Peptic Ulcer disease
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8
Q

What is the difference between cardiac and pleuritic chest pain?

A

Cardiac - From heart and causing ishaemia

Pleuritic - From pleural or pericardial sac

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9
Q

What are the features of cardiac chest pain?

A
  • Visceral chest pain (from internal organs, can be referred pain)
  • Dull, poorly localised, heavy
  • Worsened with exersion
  • Around centre of chest
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10
Q

What are the features of pleuritic chest pain?

A
  • Somatic pain (from joints, bones, muscles and soft tissues)
  • Sharp pain, often well localised
  • Worse with inspiration, coughing ir positional movements.
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11
Q

What is pericarditis?

A
  • Inflammation of the pericardium
    • more common in men and adults
  • Often secondary to a viral illness
  • Presents with chest pain
    • Retrosternal (centre and behind sternum)
    • Sharp pain, localised to front of chest
    • Aggrevated with inspiration, cough, lying flat
    • Eased with sitting up and leaning forward
    • Pericardial rub may be heard on auscultation
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12
Q

What is cardiac (Ischaemic) chest pain?

A
  • Pain secondary to pathology involvinf the heart
    • Ischaemic heart disease
  • Potentialy a life-threatening cause of chest pain
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13
Q

What is the pathophysiology of ischaemic heart disease?

A

Atherosclerosis causes ischaemic heart disease.

Atherosclerosis builds up over time. These plaques are made of a lipid-laden core with a fibrous external cap.

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14
Q

What are the risk factors of ischaemic heart disease?

A

Risk factors for atherosclerosis are also risk factors for ischaemic heart disease as atherosclerosis causes IHD.

Modifiable:

  • Smoking
  • Hypertension
  • Dyslipidaemia (Abnormal amount of lipids in the blood)
  • Diabetes
  • Obesity
  • Sedentary lifestyle

Non-modifiable:

  • Advanced age
  • Family history (of early IHD)
  • Male
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15
Q

What is stable angina?

A

Heart tissue ischaemia only occurs when the metabolic demands of cardiac muscle are treated than what can be delivered via coronary arteries e.g. on exertion

Stable angina occurs when the atherosclerotic plaque is stable.

Typical patient history:

  • Dull, central pain
  • Cone on with exersion and relieved by rest
  • May (may not) radiate to neck / shoulder
  • Not associated with autonomic features (sweating, nausea)
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16
Q

What are some acute coronary syndromes?

A

Unstable angina

Myocardial Infarction

NSTEMI (non-ST elevated MI)

STEMI (ST elevation MI)

17
Q

What are acute coronary syndromes?

A

Acute myocardial ischaemia caused by atherosclerotic coronary artery disease.

Atheromatous plaques ruptures with thrombus formation causing an acute increased occlusion (in an already partially occluded lumen) leading to ischaemia and potential infarction (myocardial tissue necrosis)

18
Q

How do acute coronary syndromes occur?

A
  1. Atherosclerotic plaque rupture
  2. Platelet addregation and formation of a thrombus
  3. Partially or Completely occlusive thrombus (the degree of occlusion depends on whcih acute coronary syndrome it is
    1. Unstable angina = Heart tissue ischaemia but no cardiac enzyme leak (partial occlusion)
    2. NSTEMI = Heart tissue death (infarction) and cardiac enzymes leak from necrosed cardiac muscle cells. (Althoguh not complete occlusion)
    3. STEMI = complete occlusion (worse of the three). Heart tissue death (infarction), Cardiac enzymes leak from necrosed cardiac muscle cells.
19
Q

What is a typically patient history of unstable angina?

A

Many similarities to stable angina.

EXCEPT:

  • Pain occurs at rest (or on very little exersion)
  • Or deteriorating symptom control
  • Pain may be more intense
  • Pain may last longer
  • There is a risk of then deteriorating more and causing an NSTEMI or a STEMI
20
Q

What is a typical patient history of an MI?

A
  • Dull, central chest pain
  • May radiate to shoulder, jaw and arm
  • Occurs at rest
  • Look unwell
  • Pain more severe than stable angina
  • Nauseous and sweaty. (ANS activation)
  • Symptoms of heart not working - breathless. (Maybe)
21
Q

What are the differences in clinical finding of Stable Angina and Acute Coronary Syndromes?

A

Stable angina

  • Clinical examination often normal
  • Will be chest pain free at rest

Acute coronary syndromes

  • Clinical examination is often normal!
  • But may appear sweaty, anxious or pale
  • +/- clinical signs secondary to complications of cardiac tissue death (NSTEMI / STEMI) e.g. acute coronary heart failute, heart murmur
22
Q

Wha diagnostic tests do you do in suspected acute coronary syndrome?

A
  • ECG
    • Changes suggestive of current ischaemia or infarct
    • Look at ST segment (elevation / depression), T waves, +/- pathological Q waves
  • Blood tests
    • Troponin
      • Presence indicates cardiac myocyte death
  • Others to exclude and complications
    • To exclude potential diagnosis
    • To identify potential complications
23
Q

What ECG changes occur in a STEMI?

A
  • Patterns of infarct
    • ST segment elevation
    • Hyperacute T waves
  • Localisation of the changes helps todetermine anatoical site
    • E.G. inferior STEMI: ST elevation seen in II, III and avF
  • New left bundle branch block
24
Q

What ECG changes occur in Unstable Angina and NSTEMI?

A
  • Patterns of ischaemia
    • ST depression
    • T wave flattening or inversion
25
Q

With similar ECG changes, how would you differentiate between UA and NSTEMI?

A

Troponin levels as these would rise in an NSTEMI but not in UA