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Periodontology > Chemotherapeutics > Flashcards

Chemotherapeutics Flashcards

1
Q

What is the chemotherapeutic agent to treat periodontitis

A

NONE – no chemothehrapeutics can treat periodontitis

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2
Q

percentage of chlorohexidine in mouthwashes available by prescription

A

0.12%

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3
Q

Mouthwashes substantivity

A

want this to be high

like chlorohexidine BINDS to some things

dont want low – because it will rinse out of the oral cavity too quickly

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4
Q

gold standard of mouth washes

A

chlorohexidine

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5
Q

gum butler version of chlorohexidine

A

no alcohol - so good for patients that are recovering alcoholics or do not want it in their wash

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6
Q

substantivity of chlorohexidine and characteristics and use

A

between 12-18 hours

2x a day
alcohol content is 12% and pH is 5.5

it is positively charged and is attracted to the surfaces of the teeth and oral soft tissues

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7
Q

middle of the road mouthwashes effects in terms of plaque

A

they have plaque inhibitory effects but LACK ANY TRUE ANTO-PLAQUE effectts

-these include listerine

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8
Q

listerine characteristics

A
  • considered an essential oil
  • 26.9% alcohol and pH of 5.0 - non prescription phenolic compound containing essential oils

-

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9
Q

active ingredient in listerine

A

essential oils

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10
Q

why alcohol in mouthwashes

A

so the active ingredients to stay effective and not denature

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11
Q

is listerine charged and implicatino

A

no - so low substantivity (unlike chlorohexidine)

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12
Q

method of action in listerine

A

alterations in the bacterial cell wall

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13
Q

method of action in listerine

A

alterations in the bacterial cell wall

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14
Q

adjunctive therapies to plaque removal

A

very limited

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15
Q

CPC?

A

active ingredient in the ‘bottom of the barrel’ of mouth washes

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16
Q

CPC?

A

Cetyl pyridinium chloride

active ingredient in the ‘bottom of the barrel’ of mouth washes

0.05% in Cepacol or scope 0.045%

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17
Q

use of iodine?

A

prevention in skin infections and treatment of wounds

  • broad spectrum bactericide - effective against yeasts, molds, bacteria,
18
Q

use of Povidone iodine?

A

prevention in skin infections and treatment of wounds

  • broad spectrum bactericide - effective against yeasts, molds, fungi, viruses and proteases
19
Q

stannous flouride

A

also the additional benefit of inhibiting plaque accumulation

20
Q

oxygenating agents

A

hydrogen peroxide and buffered sodium peroxyborate and peroxycarbonate in mouth rinses have a beneficial effect probably by inhibiting ANEROBIC bacteria

  • as obligate anerobes are important in development of gingivitis and periodontitis
21
Q

down fall of oxygenating agents

A

most bacteria that are anaerobic and involved in periodontitis are subgingival

22
Q

down fall of oxygenating agents

A

most bacteria that are anaerobic and involved in periodontitis are subgingival

23
Q

are there ADA approved products in terms of oxygenating agents

A

NO

24
Q

pre-brushing rinse?

A

no effect on plaque what so ever

25
Q

plax - active ingredient?

A

contain detergents

  • pre brush rinse
  • worthless
  • claims to loose plaque prior to brushing

7.5% alcohol

sodium benzoate and that combined with soaping agents may have a surfactant action on plaque

not ADA approved

26
Q

plax - active ingredient?

A

contain detergents

  • pre brush rinse
  • worthless
  • claims to loose plaque prior to brushing

7.5% alcohol

sodium benzoate and that combined with soaping agents may have a surfactant action on plaque

not ADA approved

27
Q

dentifrices and general use

A

toothepaste

promote oral hygiene

  • aid in removal of plaque removal from teeth
  • elimination and or masking of halitosis and as a delivery agent for active ingredients such as fluoride
28
Q

dentifrices and general use

A

toothepaste

promote oral hygiene

  • aid in removal of plaque removal from teeth
  • elimination and or masking of halitosis and as a delivery agent for active ingredients such as fluoride
29
Q

essential cleaning in tooth paste and brushing

A

more mechanical action of brushing than the paste active chemicals

30
Q

dentifrices and general use

A

toothepaste

promote oral hygiene

  • aid in removal of plaque removal from teeth
  • elimination and or masking of halitosis and as a delivery agent for active ingredients such as fluoride

so

  • minimize plaque build up
  • provide an anti-caries effect
  • remove stain
  • freshen breath
31
Q

essential cleaning in tooth paste and brushing

A

more mechanical action of brushing than the paste active chemicals

32
Q

tarter control in dentifrices?

A

tarter = calculus

33
Q

tarter aka

A

calculus

34
Q

triclosan

A

broad spectrum anit-microbrial

- can be found in mouth rinses and toothpastes in europe but ONLY AVAILABLE in COLGATE TOTAL

35
Q

COLGATE TOTAL importance

A

triclosan and its ability to be anti-gingivitis

36
Q

co-polymer with triclosan

A

protects stability of the molecule

increases the substantivity of triclosan

37
Q

COLGATE TOTAL importance

A

triclosan and its ability to be anti-gingivitis

  • paste has demonstrated anti-plaque and anti-gingivitis properties that have earned FDA approval and ADA acceptance for its ability to prevent and reduce gingivitis
38
Q

co-polymer with triclosan

A

protects stability of the molecule

increases the substantivity of triclosan

39
Q

questions about triclosan

A

chlorinated aromatics - containing one or more benzene rings with one or more chlorine atoms bound to carbon atoms

  • toxic chlorinated dioxins and furans and PCB’s
40
Q

parodontax

A

has stannous flouride which helps with plaque accumulation and claims to reduce by 40%

  • says it helps to prevent bleeding gums
  • but any toothepaste can do this as long s brushing correctly
41
Q

irrigation of the periodontal tissues?

A

never a mono-treatment

  • adjunctive therapy
  • hjelp suppress bacterial etiologic agents
  • supra- and sub- gingival irrigation is to non- specifically reduce microbial deposits that may induce periodontal diseases

Periodontology (20 decks)

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