Chemokines Flashcards

1
Q

what are they

A

small proteins that direct cell migration

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2
Q

cell trafficking determined by:

A

cytokine mileau and chemokine gradient

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3
Q

important chemokines for monocytes and macrophages

A

CCL2, CCL4, CCL5 and CCL7

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4
Q

important chemokines for neutrophils

A

CXCL 1,2,5, and 8

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5
Q

CXCL4 and 5 are structurally similar to

A

defensin and possess similar antimicrobial properties

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