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Chemotherapy > Chemo Man > Flashcards

Chemo Man Flashcards

0
Q

Neurotoxicity dose dependent

A

Ara-c

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1
Q

Neurotoxicity (dose independent)

A

Platinol

Eloxatin

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2
Q

Ara-c toxicity is seen starting at which dose

A

> 1g/cubic m

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3
Q

Visual changes, conjunctivitis

A

Ara-c

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4
Q

Ototoxicity

A

Platinol

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5
Q

Which platinum compound causes a decrease in electrolytes and light sensitivity?

A

Platinol

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6
Q

Which purine antagonist causes a syndrome that can be augmented by steroids?

A

Ara-c

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7
Q

Which anti metabolites cause mucositis

A

Adrucil

MTX

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8
Q

Which antimetabolite causes myelosuppression

A

MTX

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9
Q

Management of 5-FU mucositis is with

A

Ice chips

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10
Q

Methotrexate toxicities include:

A 
Myelosuppression 
Mucositis
Pulmonary fibrosis
Hepatic toxicity
Dose dependent renal toxicity
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11
Q

When is a leucovorin reduce used

A

Within 24 hours of high dose methotrexate therapy

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12
Q

Pulmonary fibrosis

A

MXT
Myleran
Blenoxane
Carmustine

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13
Q

Hand foot syndrome

A

5-FU

Xeloda

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14
Q

Treatment of hand foot syndrome

A

Vitamine B-6

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15
Q

Purine antagonist that causes paralysis and alopecia

16
Q

Which anti tumor antibiotic causes Hyperpigmentation, pneumonitis and has a life time max

17
Q

Which alkylating agent causes increases in uric acid

18
Q

Cardiotoxicity

A

Anthracyclines

Xeloda

19
Q

Extravasation

A

Cerubidine
Adriamycin
Vinca alkaloids

20
Q

What is the diffrence in toxicity between Xeloda and 5-FU?

A

Hand and foot: Xeloda > 5-FU

GI diarreha : 5-FU>Xeloda

21
Q

insulin dependent diabetes(Dose dependent)

22
Q

Nephrotoxic

A

Platinum compounds:
Platinol>Paraplatin-AQ
Carmustine

23
Q

What exacerbates Eloxatin induced neuropathy?

24
Q

Peripheral neuropathy

A

Vinca alkaloids
Eloxatin
Taxol

25
Q

Which vinca alkaloid is most likely to cause neuropathy

26
Q

Which vinca alkaloid is least likely to cause neuropathy

27
Q

Hepatotoxic

A

Trexall

Carmustine

28
Q

Hemorrhagic cystitis

A

Cytoxan

Mitoxana

29
Q

What is used to prevent any treat chemotherapy induced hemorrhagic cystitis?

A

Mesna and hydration

30
Q

SIADH

31
Q

Increased levels of acute and delayed emesis

32
Q

Significant early onset and lethal delayed onset diarrhea

33
Q

Treatment for early onset Camptosar diarrhea

A

1mg atropine

34
Q

What is treatment of late onset Camptosar diarrhea

A

Loparamide without a renal max

35
Q

Which vinca alkaloid causes blood dyspraxia and the most bone marrow suppression

36
Q

Which vinca alkaloid causes the least bone marrow suppression

37
Q

Which agent may cause constipation

Chemotherapy (7 decks)

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