Antimicrotubules Flashcards

0
Q

Vinca alkaloids

A

Oncovin, Vincasar
Velban
Navelbine

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1
Q

Inhibit microtubule formation

A

Vinca alkaloids

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2
Q

Oncovin, Vincasar

A

Vincristine

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3
Q

Velban

A

Vinblastine

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4
Q

Navelbine

A

Vinorelbine

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5
Q

Vinca alkaloids can only be given

A

IV ONLY

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6
Q

What kind of tubing should be used for Taxol

A

Non-PVC tubing and bag

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7
Q

What is the pretreatment regimen for taxol

A

Antiemetic + Benydril + cimetidine + 8mg dexamethasone by mouth BID for 5 days

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8
Q

What is used as pretreatment for Taxotere

A

8mg dexamethasone by mouth BID for 5 days

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9
Q

Taxotere increases _________ causing ________.

A

Fluid retention , edema

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10
Q

Inhibit the disassembly of microtubules

A

Taxanes

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11
Q

Taxanes

A

Taxol

Taxotere

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12
Q

Taxol

A

Paclitaxel

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13
Q

Taxotere

A

Docetaxel

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14
Q

What are the 4 esignificant side effects of Taxanes

A

1 neuropathy
2 anaphylaxis
3 hypotension
4 edema (angioedema)

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15
Q

Abraxane

A

Albumin bound Paclitaxel

16
Q

What is the advantage of Abaxane

A

Avoid hypersensitivity so no pre tx needed