Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Patho 2 Final > Chemo Drugs > Flashcards

Chemo Drugs Flashcards

1
Q

Cytotoxic Agents: MOA

A

Disrupt DNA synthesis

Disrupt Mitosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Alkylating Agent

A

Cyclophosphamide

Non-specific

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Cyclophosphamide: Toxicities

A
  • Vesicant
  • Hemorrhagic agent
  • Sterility
  • Discoloration of skin and nails
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Antimetabolite

A

Methotrexate

(Specific) S-phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Methotrexate

A

Resembles natural metabolite (Folate)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Methotrexate: Toxicities

A
  • Nephrotoxic
  • Hepatotoxic
  • Fetal death and abnormalities
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Antitumor Antibiotic

A

Doxorubicin
(Nonspecific)

Source: Streptomyces

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Doxorubicin: Toxicities

A
  • Cardiotoxicity (sometimes fatal)

- Can be acute or delayed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Mitotic inhibitors

A

Vincristine
(Specific)

Source: Periwinkle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Vincristine: Toxicities

A
  • No bone marrow suppression
  • Peripheral neuropathy**
  • Vesicant
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Biologics are approved for use on what type of cancers?

A 
Leukemias/lymphomas
Breast
Brain
Bladder
Colon
Lung
Pancreatic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Types of Biologics

A
  1. Immune checkpoint
  2. T-cell transfer therapy
  3. Monoclonal antibodies
  4. Treatment vaccines
  5. Immune system modulators
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Antiemetic: Dopamine Antagonist

A

Promethazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Promethazine MOA

A

Blocks dopamine receptors in the CTZ

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Promethazine: AE

A

Black Box Warnings:

  • Respiratory Depression <2yo
  • Gangrenous extravasation
  • Respiratory depression
  • Drowsiness + sedation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly

Patho 2 Final (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions