Chemical Senses Flashcards

1
Q

cAMP function

A

opens cation channel

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2
Q

Second messenger function olfactory system

A

amplify sensory signals

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3
Q

Insect olfactory receptors

A

Ion channels

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4
Q

Olfactory receptor specialisation

A

some receptors are very specialised, some very general

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5
Q

Olfactory sensory neuron maturation

A

mature neurons express a single olfactory receptor

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6
Q

How do we know mature olfactory sensory neurons only express a single neuron

A

single cell whole transcriptome sequencing

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7
Q

Olfactory convergence onto glomerulus

A

Olfactory sensory neurons expressing the same receptor converge on the same glomerulus

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8
Q

In drosophila what is the olfactory bulb the same as

A

antennal lobe

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9
Q

Olfactory bulb

A

structure in forebrain of vertebrates that receives neural input about odours

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10
Q

Sensory neurons transfer information to ?

A

second order neurons at glomeruli

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11
Q

What is the equivalent to olfactory sensory neurons in drosophila

A

olfactory receptor neurons

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12
Q

True or False - one to one between sensory neurons and second class of neurons

A

true

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13
Q

What does receptor specific matching of sensory neurons to second order neurons ensure

A

odour specificity is carried through

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14
Q

What are mitral cells and tufted cells equivalent to in drosophila

A

projection neurons

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15
Q

What do mitral and tufted cells project to

A

the brain

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16
Q

What is the first relay synapse important for - olfactory

A

transformation of the odour code

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17
Q

What is the first relay synapse between - olfactory

A

sensory neurons and second order neurons

18
Q

What synaptic adaptation emphasise

A

start of the odour

19
Q

Describe the first relay synapse - olfactory

A

rapidly adapting, weakens over time

20
Q

What does the first relay synapse (olfactory) allow

A

nervous system to focus on changes in odour

21
Q

What is the function of converging sensory neurons onto second order neurons

A

reduce noise, strengthens weak responses

22
Q

what is the function of lateral cross talk

A

gain control and de-correlation

23
Q

Lateral cross talk - gain control function

A

sensitive to very weak and very strong odours

24
Q

Lateral cross talk - de-correlation

A

make responses of neuronal population to different odours as diff as possible

25
Olfactory behaviours
learned and innate
26
Learned olfactory behaviour brain area human
piriform cortex
27
Learned olfactory behaviour brain area insects
mushroom body - kenyon cells
28
Innate olfactory behaviour humans brain area
amygdala
29
Innate olfactory behaviour brain area insects
lateral horn
30
What is required for innate odour responses humans
cortical amygdala
31
How can you show a brain region is responsible for a certain behaviour
silence that brain region
32
What are the purposes of innate and learning circuitry
innate - categorise, learned - discriminate
33
What is the difference between innate and learning circuitry activity
innate - dense, learning - sparse
34
How do bacteria move
swim straight (runs) or turns (tumbles)
35
What is the effect of increasing nutrient concentration on bacterial movement
run more, tumble less
36
What organism uses the same rule as bacteria
C.Elegans
37
How can transience be generated in olfactory stimuli
moving head
38
What receptors does taste transduction use
metabotropic and ionotropic
39
What is the function of signal transduction pathways
amplify signals
40
What does bitter inhibit
sweet
41
How does bitter inhibit sweet
lateral inhibition