chemical carcinogens (name organ and impact on that organ) Flashcards

1
Q

aflatoxins

A

LIVER - hepatocellular carcinoma

derived from aspergillus, which can contaminate stored rice and grains

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2
Q

vinyl chloride

A

LIVER - angiosarcoma

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3
Q

carbon tetrachloride

A

LIVER - centrilobular necrosis, fatty change

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4
Q

nitrosamines (smoked foods)

A

STOMACH - gastric cancer

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5
Q

cigarette smoke

A
LARYNX - squamous cell carcinoma
LUNG - squamous cell and small cell carcinoma
KIDNEY - renal cell carcinoma
BLADDER - transitional cell carcinoma
PANCREAS - pancreatic adenocarcinoma
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6
Q

asbestos

A

LUNG - bronchogenic carcinoma > mesothelioma

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7
Q

arsenic

A

SKIN - squamous cell carcinoma
LIVER - angiosarcoma
lung cancer

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8
Q

naphthalene (aniline) dyes

A

BLADDER - transitional cell carcinoma

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9
Q

alkylating agents

A

BLOOD - leukemia/lymphoma

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10
Q

alcohol

A

SCC of oropharynx and upper esophagus

hepatocellular carcinoma

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11
Q

nickel, chromium, beryllium, silica

A

LUNG carcinoma

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12
Q

IONIZING radiation (nuclear reactor accidents and radiotherapy)

A

AML
CML
papillary carcinoma of thyroid

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13
Q

NONIONIZING radiation (UVB most commonly)

A

skin - BCC, SCC, and melanoma

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