Check point inhibitors Flashcards
adverse effects of check point inhibitors
hepatitis, pneumonitis, rash, colitis, arthritis, endocrine issues
Which cancers use check point inhibitors?
metastatic melanoma, NSC lung, renal cell, other advanced cancers
How treat autoimmune adverse reactions
high dose steroids
mutation EGFR is associated with
associated with metastatic adenocarcinoma of the lung
mutation HER2 is associated with
breast and metastatic gastroesophageal
mutation BRAF is associated with
metastatic melanoma
mutation RAS is associated with
metastatic colorectal
how to treat breast metastatic gastroesophegeal
may respond to trastuzumab with chemo
how to treat metastatic melanoma
may respond to tyrosine kinase inhibitor
how to treat metastatic adenocarcinoma of lung
may respond to tyrosine kinase inhibitor
treatment of hairy cell leukemia
cladribine
malt lymphoma treatment
treat for H pylori
GIST tumor treatment
surgery and imatinib X3 years
peripheral T cell lymphoma tx
CHOP
Diffuse Large B cell tx
rituxan and CHOP
hodgkin lymphoma tx
ABVD
Burkitt lymphoma tx (starry skin on biopsy)
rituxan AND hyper CVAD
mantle cell lymphoma tx
rituxan AND hyper CVAD
limited cutaneous T cell NLH (mycosis fungiodes (expresses CD4) tx
topical steroids
renal cancer tx
nephrectomy
BRCA and advanced ovarian CA which fails three or more lines of chemo treatment
olaparib
advanced CLL in young peson
allogenic stem cell transplant
recurrent hodgkin that respondsto salvage chemotherapy
autologous stem cell transplant
