CHD Flashcards
1
Q
- Produce NO which increases cGMP in muscle cells
A
Nitrovasodilators
2
Q
- Pro-drug
- Produces NO= muscle contraction and vessel dilation
- Less resistance= reduced work for the heart
- Bloody venous system= heart fills less= reduced work out
- Sublingual tablet, nasal spray, transdermal patch
- Headaches, Dizziness, decreased BP
- Tolerance develops
- Fast- acting
A
Glyceryl trinitrate
3
Q
- HMG- CoA reductase is rate limiting step in cholesterol sythesis
- Block cholesterol production
- Reduces CHD not cure
- GI upset, abnormal liver tests, muscle problems
A
Lipid lowering drugs
4
Q
An example of a lipid lowering drug is…
A
Statins
