Chatper 10: Physiology& Histology Flashcards
Acid mantle
Protective barrier made up of sebum, lipids, sweat, and water. Has an average pH 5.5 part of the skins natural barrier function.
Barrier function
Protective barrier of the epidermis; the cot run and intercellular matrix protect the surface from irritation and dehydration.
Intercellular matrix
Lipid substances between corneum cells that protect the cells from the water loss and irritation.
Epidermal growth factor (EGF)
Stimulates cells to reproduce and heal.
Fibroblast
Cells that stimulate cells, collagen, and amino acids that form proteins.
Arrector pili muscle
Small, involuntary muscles in the base of the hair follicle that cause goose flesh when the appendage contracts, sometimes called goose bumps and papillae.
Langerhans immune cells
Guard cells of the immune system that sense unrecognized foreign invaders, such as bacteria, and then process these antigens for removal through lymph system.
Pore
Tube-like opening for sweat glands on the epidermis
Sebum
Oil that provides protection for the epidermis from external factors and lubricates both skin and hair.
Keratin
Fiberous protein of cells that is also the principle component of skin, hair, and nails; provided resiliency and protection.
Epidermis
Outermost layer of skin; a thin, protective layer with many cells, mechanisms, and nerve endings. It is made up of five layers: stratum corneum, stratum lucidum, stratum granulosum, stratum spinosum, and stratum germinativum.
Dermis
Also known as derma, corium, cutis, or true skin; support layer of connective tissue, collagen and elastin below the epidermis.
Subcutaneous layer
Also known as hypodermis; subcutaneous adipose tissue located beneath the dermis; a protective cushion and energy storage for the body.
Reticular layer
Deeper layer of the dermis that supplies the skin with oxygen and nutrients; contain fat cells, blood vessels, sudoriferous glands, hair follicles, lymph vessels, arrector pili muscles, sebaceous glands, and nerve endings.
Papillary layer
Top layer of the dermis next to the epidermis
Stratum corneum
Also known as outermost layer of the epidermis; composed of corneocytes.
Stratum granulosum
Also known as granular layer; layer of the epidermis composed of cells filled with the keratin that resemble granules; replaces cells shed from the stratum corneum.
Stratum lucidum
Clear, transparent layer of the epidermis under the stratum corneum; thickest on the palms of hands and soles of feet.
Stratum germinativum
Also known as basal cell layer; active layer of epidermis above the papillary layer of the dermis; cell mitosis takes place here that produces new epidermal skin cells and is responsible for growth.
Stratum spinosum
Also known spiny layer; layer of the epidermis above the stratum germinativum layer containing desmosomes, the intercellular connections made of proteins.
Leukocytes
White blood cells that have enzymes to digest and kill bacteria and parasites. These white blood cells also respond to allergies.
Elastin
Protein fiber found in the dermis; gives skin its elasticity and firmness.
Apocrine glands
Coiled structures attached to hair follicles found in the underarm and genital areas that secrete sweat.
Eccrine glands
Sweat glands found all over the body with openings on the skins surface through pores; not attached to hair follicles, secretions do not produce an offensive odor.
Ceramides
Glycolipid materials that are a natural part of skins intercellular matrix and barrier function.
Glycation
Caused by an elevation in blood sugar, glycation is the binding of protein molecule to a glucose molecule resulting in the formation of damaged, nonfunctioning structures, known as Advanced glycation end products. It alters protein structures and decreases biological activity.
Telangiectasia
Capillaries that have been damaged and are now larger, or distended, blood vessels; commonly called couperose skin.
Rosacea
Chronic condition that appears primarily on the cheeks and nose and is characterized by flushing, telangiestasis, and in some cases, the formation of papules and pustules.
Adipose tissue
A specialized connective tissue considered fat. Gives smoothness and contour to the body and cushions and insulates the body.
Free radicals
Unstable molecules that cause inflammation, disease, and biochemical aging in the body; especially wrinkling and sagging of the skin.