chapter seven endocrine system Flashcards
hormone
chemical messengers secreted into the blood by specialized epithelial cells
polar hormones
water-soluble, hydrophilic (peptides, catecholamines)
non-polar hormones
lipid-soluble, hydrophobic (steroids, thyroid hormones)
major classes of hormones
amines, peptides, steroids
amines
derivates of tyrosine (thyroid hormones- T3 & T4, catecholamines- Epi, NorEpi, dopamine)
peptides
AA chains / small peptides (insulin, glucagon)
steroids
derivates of cholesterol, adrenal hormones & gonadal hormones
adrenal hormones
mineralocorticoids (affect mineral metabolism) & glucocorticoids (affect glucose metabolism)
gonadal hormones
testosterone, estradiol, progesterone
goiter
enlargement of thyroid gland due to lack of iodine (don’t see this anymore due to adding iodine to salt)
where is the only place in the body iodine is found?
thyroid
hormonal transport
- peptide & catecholamines
- thyroid & steroids
peptide & catecholamines hormonal transport
water soluble, easily transported in blood, easily degraded by enzymes (short half-life)
thyroid & steroids hormonal transport
lipid soluble, small amounts free in plasma (mostly carried by transport proteins), not readily degraded by enzymes (long half-life), medication
peptide & catecholamines hormonal action
must act on extracellular receptor, activating an enzyme or a second messenger system