Chapter 9: The Digestive System Flashcards
Enteric nervous system
Collection of one hundred million neurons that governs the function of the GI system; present in the walls of the digestive tract and trigger peristalsis; can function independently of the CNS although it is heavily regulated by the autonomic nervous system
Parasympathetic control of the ENS
Stimulation of digestive activities, increasing secretions from exocrine glans and promoting peristalsis
Parts of the pharynx
Nasopharynx; oropharynx, and the laryngopharynx
Anatomical divisions of the stomach
Fundus and body (contain mostly gastric glands) and the antrum and pylorus (contain mostly pyloric glands)
Gastric glands
Respond to signals from the vagus nerve of the parasympathetic nervous system; activated by the brain in response to the sight, taste, and smell of food
Cell types of gastric glands
Mucous cells - produce bicarbonate-rich mucus that protects the muscular wall from the harshly acidic (pH = 2) and proteolytic environment of the stomach
Chief cells - secrete pepsinogen
Parietal cells - secrete hydrochloric acid that cleaves pepsinogen into pepsin
Pepsin
Cleaves peptide bonds near aromatic amino acids, resulting in shorter peptide fragments
Intrinsic factor
Secreted by parietal cells; a glycoprotein involved in proper absorption of vitamin B12
Pyloric glands
Contain G cells that secrete gastrin
Gastrin
Induces the parietal cells in the stomach to secrete more HCl and signals the stomach to contract, mixing its contents
Chyme
Acidic, semifluid mixture; combined mechanical and chemical digestive activities of the stomach result in a significant increase in the surface area of the now unrecognizable food particles
How long is the small intestine?
7 meters
Duodenum
Responsible for the majority of chemical digestion and has some minor involvement in absorption
Jejunum and ileum
Majority of absorption
Enteropeptidase
Involved in the activation of other digestive enzymes (trypsinogen and procarboxypeptidases A and B) from the accessory organs of digestion; secreted by the duodenum along with secretin and cholecystokinin
Secretin
Peptide hormone that causes pancreatic enzymes to be released into the duodenum; regulates pH in the duodenum by reducing HCl secretion from parietal cells and increasing bicarbonate secretion from the pancreas; enterogastrone that slows motility through the digestive tract (increases the time for digestive enzymes to work on fats)
Cholecystokinin
Secreted in response to the entry of chyme into the duodenum (especially amino acids and fats); stimulates the release of both bile and pancreatic juices and also acts in the brain where it promotes satiety
Functions of the liver
Processing of nutrients (glycogenesis and glycogenolysis, storage and mobilization of fats, gluconeogenesis), production of urea, detoxification of chemicals, production of bile and synthesis of albumin and clotting factors
Bilirubin
Byproduct of the breakdown of hemoglobin
Gallbladder
Located just beneath the liver and both stores and concentrates bile; upon release of CCK, the gallbladder contracts and pushes bile out into the biliary tree; common site of cholesterol or bilirubin stone formation
What are the three sections of the large intestine
Cecum (with the appendix and receives fluid exiting the small intestine through the ileocecal valve); colon (ascending, transvserse, descending, sigmoidal); rectum (storage site for feces_