Chapter 9 - Glycolysis Flashcards

1
Q

Glycolysis

A

Catabolic pathway of glucose oxidation to pyruvate

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2
Q

Glucose

A

C6H12O6

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3
Q

O-glycosidic Bond

A

Covalent bond links monosaccharides together through O

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4
Q

Pyruvate Aerobic

A

ATP production through the citric acid cycle and ETC

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5
Q

Pyruvate Anaerobic

A

Lactate production, ethanol production

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6
Q

Anaerobic 2

A

C6H12O6 + 2NAD + 2ADP + 2Pi >< 2Pyruvate + 2NADH + 2H + 2ATP + 2H2O

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7
Q

Step 1

A

Phosphorylation of glucose by hexokinase/glucokinase

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8
Q

Step 2

A

Isomerization of glucose-6TP to fructose-6-P by phosphoglucoisomerase

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9
Q

Step 3

A

Phosphorylation of fructose-6-P to fructose-1,6-BP by phosphofructokinase

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10
Q

Step 4

A

Cleavage of fructose-1,6-BP into glyceraldehyde-3-P/dihydroxyacetone by aldolase

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11
Q

Step 5

A

Isomerization of dihydroxyacetone-P to glyceraldehyde-3-P by triose phosphate isomerase

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12
Q

Step 6

A

Oxidation/phosphorylation of glyceraldehyde-3-P to form 1,3-bisphosphoglycerate by glyceraldehyde-3-P dehydrogenase

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13
Q

Step 7

A

Substrate-level phosphorylation to generate ATP in conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate by phosphoglycerate kinase

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14
Q

Step 8

A

Phosphoryl shift in 3-phosphoglycerate to form 2-phosphoglycerate by phosphoglycerate mutase

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15
Q

Step 9

A

Dehydration of 2-phosphoglycerate to form phosphoenolpyruvate by enolase

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16
Q

Step 10

A

Substrate-level phosphorylation to generate ATP in conversion of phosphoenolpyruvate to pyruvate by pyruvate kinase

17
Q

Regulation

A

Based on the supply-demand of glycolytic intermediates