Chapter 10 - Citrate Cycle Flashcards

1
Q

Citrate Cycle

A

Control pathway in oxidative respiration, converts acetyl units to CO2 with the production of FADH2, NADH, and ATP

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2
Q

Product

A

3 NADH, 1 FADH2, 1 GTP, transfer 8 electrons

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3
Q

Redox Reaction

A

Acetyl-CoA + 3NAD + FAD + GDP + Pi + 2H2O > CoA + 2CO2 + 3NADH + 3H + FADH2 + GTP

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4
Q

Pyruvate Dehydrogenase

A

Converts pyruvate to acetyl-CoA, necessary transition from glycolysis

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5
Q

Step 1

A

Acetyl-CoA + Oxaloacetate + H2O (citrate synthase)> CoA + citrate

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6
Q

Step 2

A

Citrate (aconitase)>< Isocitrate

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7
Q

Step 3

A

Isocitrate + NAD (isocitrate dehydrogenase)> a-Ketoglurate + NADH + CO2 + H

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8
Q

Step 4

A

a-Ketoglurate + CoA + NAD (a-ketoglutarate dehydrogenase)> Succinyl-CoA + NADH + CO2 + H

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9
Q

Step 5

A

Succinyl-CoA + GDP + Pi (succinyl-CoA synthetase)>< Succinate + GTP + CoA

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10
Q

Step 6

A

Succinate + FAD (succinate dehydrogenase)>< Fumarate + FADH2

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11
Q

Step 7

A

Fumarate + H2O (fumarase)>< Malate

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12
Q

Step 8

A

Malate + NAD (malate dehydrogenase)>< Oxaloacetate + NADH + H

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