Chapter 17 - Amino Acid Metabolism Flashcards
Assimilation
Glutamate and glutamine provide nitrogen
Fixation
Reduces nitrogen (N2) to NH3/NH4+
Amino Acid Degradation
NH4+ transport to liver and turned into urea for excretion, continuous due to short enzyme half-life
Amino Acid Synthesis
Derived from 7 metabolic intermediates from glycolysis, PPP, and citrate cycle
Transanimation
Amino group transfers from one molecule to another
Nitrogenase
Enzyme that catalyzes nitrogen fixation
Nitrification
Oxidation of reduced nitrogen to nitrite/nitrate
Ammonia Assimilation
NH4+ into glutamate and glutamine
11 of 20 amino backbones converted to
Pyruvate and acetyl-CoA
Pentose Phosphate Pathway Intermediates:
Ribose-5-phosphate, enythrose-4-phosphate
Citrate Cycle Intermediates:
Oxaloacetate and a-ketoglutarate
Glycolytic Pathway Intermediates:
3-phosphoglycerate, phosphoenolpyruvate, and pyruvate
Glutamate metabolized by ______, to release NH4+ for urea synthesis
Glutamate dehydrogenase