Chapter 9

Question 1

Allosterism

Answer 1

A change in the activity & conformation of an enzyme resulting from the binding of a compound at a site on the enzyme other than the active binding site.

Question 2

Allosteric Sites

Answer 2

The place on an enzyme where a molecule that is not a substrate may bind, thus changing the shape of the enzyme & influencing its ability to be active.

Question 3

Negative Allosterism

Answer 3

Occurs when the binding of one ligand decreases the affinity for substrate of other active sites.

Question 4

Feedback Regulation

Answer 4

Control mechanism that uses the consequences of a process to regulate the rate at which the process occurs.

Question 5

Secondary Messengers

Answer 5

Molecules that relay signals received at receptors on the cell surface.

Question 6

Covalent Modification

Answer 6

Enzymes can be regulated by transfer of a molecule or atom from a donor to an amino acid side chain that serves as the acceptor of the transferred molecule.

Question 7

Proenzymes

Answer 7

An inactive enzyme precursor.

Also called a Zymogen