Chapter 9 Flashcards

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1
Q

Protein Sythesis

A

the process of using instructions carried on a gene to create proteins

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2
Q

Gene

A

a sequence of DNA that encodes a protein

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3
Q

Protein

A

a large molecule composed of amino acids

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4
Q

DNA

A
  • Double-stranded
  • Each nucleotide composed of deoxyribose, phosphate, and nitrogenous base
  • 4 bases: adenine, thymine, guanine, cytosine
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5
Q

RNA

A
  • Single-stranded
  • Nucleotides comprised of ribose, phosphate, and nitrogenous base
  • 4 bases: A, T, G, and Uracil
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6
Q

Transcription

A

DNA to RNA

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7
Q

Translation

A

RNA to Protein

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8
Q

RNA Polymerase

A
  • Binds to the promoter region of the gene

- Zips down the length of gene, matching RNA nucleotides with complementary DNA nucleotides

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9
Q

Ribosomes

A

is composed of ribosomal RNA (rRNA) and comprises a small and a large subunit

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10
Q

Transfer RNA

A

tRNA carries amino acids and matches its anticodon with codons on mRNA

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11
Q

Mutations

A

changes in genetic sequence

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12
Q

Base-Substitution Mutation

A

simple substitution of one base for another

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13
Q

Neutral Mutation

A

mutation does not change the function of the protein, it codes for the same amino acid

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14
Q

Frameshift Mutation

A

addition or deletion of a base, which changes the reading frame

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15
Q

Regulating Gene Expression

A

turning a gene or a set of genes on or off

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16
Q

Repressors

A
  • Bind to the promoter and prevent the RNA polymerase from binding
  • Prokaryotic cells use to regulate gene expression
17
Q

Activators

A
  • Help the RNA polymerase bind to the promoter

- Eukaryotic cells use activators to regulate gene expression

18
Q

Transgenic Organism

A

the result of the incorporation of a gene from one organism to the genome of another (genetically modified organism (GMO))

19
Q

Gene Therapy

A

replacement of defective genes with functional genes

20
Q

Germ Line Gene Therapy

A
  • Embryonic treatment
  • Embryo supplied with a functional version of the defective gene
  • Embryo + cells produced by cell division have a functional version of gene
21
Q

Somatic Cell Gene Therapy

A

fix or replace the defective protein only in specific cells

22
Q

SCID

A

severe combined immunodeficiency

23
Q

Nuclear Transfer

A

cloning is achieved through this process