Chapter 8 Study Questions (Part 3) Flashcards
explain the following sentence: binding 1) excitatory neurotransmitters to their 2) postsynaptic receptors triggers a 3) graded excitatory postsynaptic potential.
excitatory neurotransmitters: let (+) ions in, depolarized
postsynaptic receptors: other side of the synapse
graded excitatory postsynaptic potential: depolarization, towards the positive
explain the difference between an ionotropic and metabotropic ligand-gated receptor
ionotropic: fast ligand-gated channel
metabotropic: G protein
what is an ionotropic receptor
fast ligand-gated ion channel
what is a metabotropic ligand-gated receptor
G protein
T or F: EPSPs and IPSPs can occur at the same time on the same neuron
true. that’s what we’ve been getting at!
what is an EPSP
excitatory postsynaptic potential
what is an IPSP
inhibitory postsynaptic potential
what is summation?
adding the effect of neuron firing
what is the difference between temporal and spatial summation?
temporal: multiple firings of the same neuron
spatial: lots of neurons in space, firing at the same time on the same postsynaptic neuron
give an example of temporal summation
only A is firing –> Na+ influx (graded potentials)
give an example of spatial summation
multiple presynaptic neurons fire very close together in time
what is divergent and convergent neural integration?
DIV: one neuron talks to many neurons
CONV: many neurons converge on one neuron
what is divergent integration?
DIV: one neuron talks to many neurons
what is convergent integration?
CONV: many neurons converge on one neuron
how does an axoaxonic synapse stimulate or inhibit a presynaptic axon terminal?
inhibitory + excitatory: less NT than normal released
excitatory + excitatory: more NT than normal released
