Chapter 8 - Anesthesia Flashcards
MAC (minimum alveolar concentration) equals what?
Smallest concentration of inhalation agent at which 50% of patients will not move with incision
Small MAC means what?
More lipid soluble = more potent = slow speed of induction
Effects of inhalational agents?
Unconsciousness, amnesia, some degree of analgesia
Side effects of inhalational agents?
Blunted hypoxic drive, myocardial depression, increased cerebral blood flow, decreased renal blood flow
Characteristics of NO2?
Fast, minimal myocardial depression
Characteristics of halothane?
Slow, highest degree of cardiac depression and arrhythmias, least pungent (good for kiddies)
What is halothane hepatitis?
Fever, eosinophilia, jaundice, increased LFTs
Side effect of enflurane?
Seizures
Characteristics of sevoflurane?
Less myocardial depression, fast on/off, less laryngospasm, higher cost
Side effects of sodium thiopental (barbiturate)?
Decreased cerebral blood flow and metabolic rate, decreased blood pressure
Characteristics of propofol?
Very rapid distribution and on/off, amnesia, sedative; NOT an analgesic
Side effects of propafol?
Hypotension, respiratory depression; do not sure in pts with egg allergy
Characteristics of ketamine?
Dissociation of thalamic/limbic systems, places pts in cataleptic state (amnesia, analgesia); no respiratory depression
Side effects of ketamine?
Hallucinations, catecholamine release (inc. CO and tachycardia), inc. airway secretions, inc. cerebral blood flow (contraindicated in head injuries)
Characteristics of etomidate?
Fewer hemodynamic changes, fast acting
Side effect of etomidate?
Continuous infusions can lead to adrenocortical suppression
What is the last muscle to go down and 1st to recover from paralytics?
Diaphragm
What is the 1st muscles to go down and last to recover from paralytics?
Neck and face muscles
What is the only depolarizing agent?
Succinylcholine
Characteristics of succinylcholine?
Fast, short acting; causes fasciculations
Side effects of succinylcholine?
Malignant hyperthermia, inc. ICP, incraed end-tidal CO2 then fever, tachycardia, rigidity, acidosis, hyperkalemia