Chapter 8: An Introduction to Metabolism Flashcards
metabolism
totality of CR, consisting of catabolic and anabolic pathways, and manage the material and energy resources of the organism
metabolic pathway
series of CR that build (anabolic) a complex molecule or break down (catabolic) a complex molecule to simpler molecules
catabolic pathway
metabolic pathway that releases energy by breaking down complex molecule into simpler ones
anabolic pathway
metabolic pathway that consumes energy to make complex molecules
bioenergetics
the overall flow and transformation of energy through an organism, the study of how energy flows through an organism
energy
capacity to cause change, especially to do work (to move matter against an opposing force)
kinetic energy
energy from movement of ions
thermal energy
random movement resulting in energy
potential energy
potential for energy, stored energy
chemical energy
energy from chem reactions
first law of thermodynamics
energy cannot be created or destroyed, only transferred or transformed (conservation of energy)
second law of thermodynamics
every transfer or transformation of energy increases the entropy of the universe. usable forms of energy are at least partly converted to heat.
exergonic reaction
spontaneous chemical reaction that there is a net release of free energy
endergonic reaction
nonspontaneous chemical reaction in which free energy is absorbed from the surroundings
adenosine triphosphate
atp, adenine-containing nucleoside triphosphate that releases free energy when its phophate bonds are hydrolyzed. Drives endergonic reactions.
catalyst
chemical agent selectively increases the rate of a reaction w/o being consumed by the reaction
enzyme
protein, speeds chemical reactions, can be used over and over and over again
substrate
substance that combines with the enzyme (at the active site) to make the chem reaction happen
ex. lactose (substrate) and lactase (enzyme)
enzyme-substrate complex
temporary complex formed when an enzyme binds to its substrate molecule
cofactor
nonprotein molecule or ion that binds to the enzyme’s active site for proper functioning of an enzyme (sometimes permanently bound, or losely bound during catalysis)
coenzyme
an organic molecule serving as a cofactor. Most vitamins act as co-enzymes in metabolic reactions.
competitive inhibitors
reduces the activity of an enzyme by entering the active site in place of the substrate, whose structure it mimics
noncompetitive inhibitors
substance that reduces the activity of an enzymes by binding to a remote location from the active site, changing the enzymes shape so the active site no longer effectively catalyzes the conversion of the substrate to product
feedback inhibition
method of metabolic control in which the end product of a metabolic pathway acts as an inhibitor of an enzyme within that pathway