Chapter 7: STI Infections Flashcards
Primary prevention of STI’s = ?
Preventing any infection! EDUCATION
Secondary prevention of STI’s = ?
Prompt Tx of the STI
Risk reduction measures for STI’s & STD’s
- knowledge of partner
- Reduction in the number of partners
- Condom use
- Negotiation of use
- Low-risk sex
- Avoiding exchange of body fluid
- Vaccination (HPV ages 8-9, guardacil-9, Hep B)
Research now shows that N-9 lubricated condoms and spermicides are NOT recommended for what ?
The prevention of HIV & STI’s
What is the most common bacterial infection ?
Chlymidia
What is the oldest bacterial communicable disease in the US ?
Gonorrhea
What are Bacterial STI’s ?
- Chlamydia
- Gonorrhea
- Syphilis
- Pelvic Inflammatory Disease
_______ (Bacterial STI), is transmitted by entry into subcutaneous tissue through microscopic abrasions that can occur during sexual intercourse ?
Syphilis
Syphilis can also be transmitted through what ?
- Kissing
- Biting
- Oral - genital sex
True or False: With Syphilis, transplacental transmission may occur at any time during pregnancy ?
True
________ (Bacterial STI) can lead to serious systemic disease and even death ?
Syphilis
In terms of pregnancy, Syphilis can cause things such as ?
- PTL (Pre-term Labor)
- PTB (Pre-term Birth)
- etc,.
Primary Syphilis (1 sore) typically starts to appear when ?
5 - 90 days
Secondary Syphilis (multiple sores) starts to appear when ?
6 weeks to 6 months
True or False: Pregnant women are screened for Syphilis ?
True
Serologic tests (can be false positives) & Microscopic exam of the lesions are screenings utilized for what Bacterial STI ?
Syphilis
What is the Drug of choice for the management of Syphilis ?
Penicillin
other drugs available, if allergic
True or False: When treating someone for Syphilis, their partners should also be treated ?
True
True or False: You should remain sexually abstinent during the treatment of Syphilis ?
True
What is the most common and fastest spreading STI ?
Chlamydia
_________ (Bacterial STI) infections are often silent and highly destructive ?
Chlamydia
What Bacterial STI is difficult to diagnose ?
Chlamydia
With Chlamydia, what type of people do we screen ?
Symptomatic & pregnant women
Why do we screen pregnant women for Chlamydia ?
Because we don’t want babies to get it
What WAS the Gold standard for diagnosing Chlamydia ?
Cultures
Now, what is the preferred method for the screening/diagnosis of Chlamydia ?
Nucleic acid test-urine and blood testing (NAAT)
What is the Management of Chlamydia focused on ?
Treatment & Rest
What drug is used to treat Chlamydia (if not pregnant) ?
Doxycycline
- Azithromycin –> if pregnant
True or False: With Chlamydia, your partner should be treated ?
True
How is Gonorrhea transmitted ?
- genital to genital
- Oral to genital
- Anal to genital
- Mother to newborn
True or False: Men may have more symptoms than women ?
True
With gonorrhea, 80% of women are what ?
asymptomatic
Risk factors for Gonorrhea ?
- Age
- African American (most cases reported)
- Early onset of sexual activity
- Multiple partners
The symptoms listed below correlate with what Bacterial STI ?
- Women are often asymptomatic
- Purulent discharge (not seen often)
- Menstrual irregularities
- Pelvic or abdominal pain
- Rectal complications
Gonorrhea
True or False: In pregnancy, Gonorrhea can affect the mother and fetus ?
True
Gonorrhea in pregnancy can cause things like what ?
- PROM (premature rupture of membranes)
- PTL (pre-term labor)
- PTB (pre-term birth)
- Uterine infection
- IUGR (Intrauterine growth retardation)
Newborns, who’s mothers have Gonorrhea during pregnancy have the potential to develop what ?
Ophthalmic Neonatorum (eye infection)
What is Ophthalmic Neonatorum ?
And what can it lead to. ?
Eye infection
Can lead to blindness
What does the CDC recommend for screening for Gonorrhea ?
- Screen all at risk women
- Screen All pregnant women
What is the Gold Standard for screening for Gonorrhea ?
Cultures
True or False: The management for Gonorrhea is straightforward and has a rapid cure ?
True
What is the Treatment for Gonorrhea ?
Ceftriaxone and Azithromycin
can get 1 Treatment or weekly
True or False: In people with Gonorrhea, their partners should also be cultured and treated ?
True
What type of bacterial STI, is an infectious process that involves the uterus, Fallopian tubes, possibly ovaries, and peritoneal surfaces ?
Pelvic Inflammatory Disease
_________________________ (Bacterial STI) results from ascending spread of microorganisms from the vagina and endocervix to the upper genital tract ?
Pelvic Inflammatory Disease
Below, are Risk factors for what Bacterial STI ?
- Hx of STI’s
- Multiple partners**
- High rates of new partners
- Untreated STI’s**
- IUD’s (increased risk for 3 weeks after insertion)
Pelvic Inflammatory Disease
What Bacterial STI put’s you at increased for…
- Ectopic pregnancy
- Infertility
- Chronic pelvic pain
- Dysparunia, pelvic adhesions, pus in uterus (pyosalpinx)
Pelvic Inflammatory Disease (PID)
Below are symptoms of what Bacterial STI ?
- Bilateral sharp, cramping pain in the lower quadrants
- Fever greater than 100F
- Chills
- Cervical or vaginal discharge
- Irregular bleeding
- Cervical motion tenderness during intercourse
- Malaise
- N & V
Pelvic Inflammatory Disease (PID)
True or False: PID is hard to treat ?
True
Why is PID hard to treat ?
Because there is no one test! Because it is a combination of diseases/infections
What is the management for PID ?
- Prevention
- Medication
- Hospitalization
- Education
HPV is what type of STI’s ?
Viral
What is the most prevalent viral STI seen in ambulatory health care settings (urgent cares) ?
HPV
True or False: HPV is a highly contagious viral STI ?
True
HPV is more frequent in who ?
pregnant women
True or False: HPV lesions enlarge during pregnancy ?
Ture
What is the primary cause of cervical cancer ?
HPV
What is the C/O of HPV ?
Profuse irritating vaginal discharge
What are others signs/symptoms of HPV ?
- Itching
- “bumps” on labia
- Dysparunia (painful intercourse)
- Vaginal bleeding
- Lesions
True or False: Some Pap smears can detect BOTH abnormal cells AND HPV ?
True
How is screening done for HPV ?
- Hx of known exposure
- Physical inspection*** (looking for warts)
- Pap smear (generally show abnormal cells)
True or False: No cure has been shown to eradicate HPV ?
True
What is the medication for HPV used for ?
For Discomfort
True or False: If you have HPV, your partner should also be examined ?
True
True or False: Sometimes HPV resolves on its own in young women ?
True
True or False: There are vaccines for the management of HPV ?
True
What is a medication that may be used in the management of HPV ?
Guardacil 9
Genital herpes is what type of STI ?
Viral
What is the abbreviation of Genital herpes simplex virus ?
HSV
Herpes simplex virus 1 (HSV-1) is transmitted how ?
Non-sexually
Herpes simplex virus 2 (HSV-2) is transmitted how ?
Sexually
The initial infection of HSV is characterized by what ?
- Multiple painful lesions
- Fever
- Chills
- Malaise
- severe dysuria
Primary genital herpes lesions progress from _________ to _________ to __________ to_________ and _____ that _______ and ______ ?
Macules --> Papules --> Vesicles--> Pustules and Ulcers --> that Crust and Heal
True or False: The ulcers from HSV are…
- tender
- edematous
- itchy
- painful
True
True or False: With HSV, maternal infection can have adverse effects on both the mother and baby ?
True
True or False: With HSV, there are increased miscarriage rates in the first trimester ?
True
True or False: With HSV, an association with cervical cancer has been observed ?
True
but primary way is HPV
True or False: Pt’s who get HSV for the 2nd or 3rd time may feel tingling even in the perineal area ?
True
Can a pregnant women with HSV, deliver her baby vaginally ?
NO !!!!!
In pregnant women with HSV, why do they plan a C-section for the delivery method ?
Because you don’t want the baby coming into contact with the lesions !
How do they screen/diagnose Herpes ?
Hx and physical exam
Is there a cure for Herpes ?
No
True or False: With Herpes, Antiviral meds are given to control symptoms ?
True
What are examples of Antiviral meds used to control the symptoms of Herpes ?
- Acyclovir
- Valtrex
With Herpes, how many times a day should you clean the lesions ?
BID
In what non pharmacological ways can Herpes be managed ?
- Sitz baths
- Oatmeal soaks
- Tea bags
True or False: Oral analgesics can be used in the management of Herpes ?
True
True or False: The management of Herpes can be chronic or recurrent ?
True
What is the most threatening Hepatitis to the fetus and neonate ?
Hepatitis B
True or False: With Hepatitis B, disease of the liver is often a silent infection ?
True
How is Hepatitis B transmitted ?
- Parenterally
- Perinatally
- Orally (rarely)
- intimate contact
What populations are at risk for Hepatitis B ?
- Asians
- Pacific Island
- Alaskan descent
- Haitian
- Sub-sahara African
Other people at risk for Hepatitis B, include those with what medical ailments ?
- Liver disease
- Dialysis patients
- Women in mentally challenged instituations
- Multiple sex partners
- IV drug users
- Healthcare workers
When are babies vaccinated against Hepatitis B ?
Immediately in the Hospital ! with the follow up injections taking place in the Dr. office on future visits
Who is screened for Hepatitis B ?
- Regular screenings for high risk individuals
- All pregnant women
What is the management for Hepatitis B ?
- Hep B vaccine
- Counciling and education
True or False: their is no specific treatment for Hep B ?
True
With HIV, what is now considered the most common means of transmission in women ?
Heterosexual transmission
The transmission of HIV occurs primarily through ?
Exchange of Body Fluids
- semen
- blood
- vaginal secretions
Once HIV is in the bloodstream, Seroconversion occurs when ?
in 6 -12 weeks
At risk behaviors of HIV include ?
- Multiple partners
- IV drug use
- Hx of multiple STI’s
What does the screening/diagnoses look like for HIV ?
- Antibody testing
- CDC advocates for routine voluntary testing
True or False: HIV testing is offered early sin pregnancy ?
True
What is the preferred method for testing for HIV ?
Rapid testing
True or False: Perinatal transmission has decreased with HIV due to antiretroviral prophylaxis ?
True
With HIV antiretroviral prophylaxis is usually started when ? And continued through ?
- Usually started after the first trimester
- Continued throughout pregnancy
What is a major side effect with HIV in pregnancy ? (antiretroviral prophylaxis ?)
Bone marrow suppression
In pregnant women with HIV, a cesarean birth should be scheduled for when ?
at 38 weeks
- Because its an environment where the amount of blood can be controlled. (I.e. utilizing suction)
Should pregnant women with HIV avoid breastfeeding ?
Yes !
______ ________ is a syndrome in which normal H2O2-producing lactobacilli are replaced with high concentrations of aerobic bacteria ?
Bacterial vaginosis (BV)
What vaginal infection is associated with preterm labor and birth ?
Bacterial vaginosis
With what type of Vaginal infection, do women complain of a “fish odor” ?
Bacterial vaginosis
What is the most common type of vaginitis ?
Bacterial vaginosis
What type of vaginal infection has discharge that is profuse whiter, grey, or milky ?
Bacterial vaginosis
How is bacterial vaginosis diagnosed ?
By clue cell findings in the vagina
What is the Tx for Bacterial vaginosis ?
Often Flagyl (metronidazole)
What is the common medication ending that is used for a lot of vaginal infections ?
“azole”
Ex: metronid”azole” (flatly)
What is the second most common type of vaginal infection ?
Vulvovaginal Candidiasis, or yeast infection
Vulvovaginal Candidiasis (VVC) can be what type of infection ?
Fungal or Yeast infection
When does Vulvovaginal Candidiasis occur ?
When new yeast is introduced or more yeast is present in the vagina
What type of vaginal infection has discharge that is Thick and white, and looks like cottage cheese ?
Vulvovaginal Candidiasis (VVC)
What are manifestations of Vulvovaginal Candidiasis (VVC) ?
- Severe itching
- Dysuria
- Dyspareunia
- Edema
How Is Vulvovaginal Candidiasis Diagnosed ?
- Exam
- Wet smear
(Will see bud like branches)
How is Vulvovaginal Candidiasis Treated ?
- Fluconazole (Diflucan)
- Miconazole cream (Monistat)
With what type of type of vaginal infection should you think of “bud like branching” ?
Yeast
What are factors affecting predisposal to Candidiasis ?
- Antibiotic therapy
- Diabetes
- Pregnancy
- Obesity
- Diets high in refined sugars
- Use of corticosteroids
- Immunosuppressed states
** A common factor in all of these except the first one = Environments with high amounts of sugar **
___________ is a vaginal infection and STI and is a common cause of vaginal infections ?
Trichomoniasis
What are the manifestations of Trichomoniasis ?
- Inflammation of the vulva and vagina
- Puritis
- Copius frothy yellow-green discharge
What is the recommended test to diagnose Trichomoniasis ?
NAAT (is the most sensitive)
What other ways is Trichomoniasis screened ?
- Speculum examination
(very uncomfortable b/c of swelling, itching, etc.) - Pap smear
How is Trichomoniasis Managed/Treated ?
Metronidazole (2g orally in a single dose)
True or False: The partners of someone with Trichomoniasis should also be treated ?
True
Why should the partner of someone diagnosed with Trichmoniasis be treated ?
B/c the Trichomoniasis infection can harbor in the urethra of males, so they have the potential to keep spreading it
______ ___ ___________ is considered normal flora in the non-pregnant women ?
Group B Streptococci
True or False: Group B Strepococci is a concern in pregnancy ?
True
Why is Group B Streptococci a concern in pregnancy ?
B/c there is an increased risk for preterm labor and transmission to the newborn
True or False: With Group B Streptococci, there is screening in pregnancy ?
True
When is Group B Streptococci treated in pregnancy ?
Treated in labor and delivery
- treated with IV penicillin before you deliver the baby*
( treating mom in L&D, but not the baby)
Is a pregnant women with Group B Streptococci, required to have a C-section ?
No !
With Group B Streptococci, There is a risk of _____ for the neonate ?
GBS
What are key STI-prevention strategies ?
Risk-reduction
Prevention of mother-to-newborn HIV transmission is most effective when ?
When the women receives antiretroviral drugs during pregnancy, labor and birth, and when the infant receives the drugs after birth.
_________ has reemerged as a common STI, affecting African American women more than any other racial or ethnic group ?
Syphilis
Effective screening by health care providers requires what ?
An open discussion about sexual orientation in an accepting manner
Women who have sex with women are at risk for what type of infections ?
Bacterial, viral, and protozoal infections
Person’s in what community are at risk for STI’S ?
LGBT community
_________ is the most common STI in women in the United States and is the most common cause of PID ?
Chalmydia
Viral Hepatitis has several forms of transmission, but _____ infections carry the greatest risk ?
HBV
What type of individuals are at the greatest risk for STI’s and HIV ?
Young, sexually active women who do not practice risk reducing sexual behaviors and who have multiple partners
______ are responsible for substantial mortality and morbidity, great personal suffering, and heavy economic burden in the Unites States ?
STI’s
True or False: Both mother and baby should be considered when the pregnant women contract an infection ?
True