Chapter 7 | Principles of Pathophysiology Flashcards
• The cell, cellular metabolism, and results of the alteration of cellular metabolism • The cardiopulmonary system and its combined respiratory and cardiovascular functions • The respiratory system and the importance of oxygenation and ventilation • The cardiovascular system and the movement of blood • The principles of perfusion, hypoperfusion, and shock • Disrupted physiology of major body systems
Define:
mitochondria
powerhouse of the cell
Define:
metabolism
the cellular function of converting nutrients into energy
Define:
aerobic metabolism
(efficient or inefficient)
the cellular process in which oxygen is used to metabolize glucose
efficient (little waste)
Define:
anaerobic metabolism
(efficient or inefficient)
the cellular process in which glucose is metabolized into energy without oxygen
inefficient (much waste)
Define:
electrolytes
a substance that, when dissolved in water, separates into charged particles
Define:
FiO₂
“fraction of inspired oxygen”
the concentration of oxygen in the air we breathe
Define:
patent
(PAY-tent)
open and clear
free from obstruction
Define:
tidal volume
the volume of air moved in one cycle of breathing
Define:
minute volume
the amount of air breathed in and out in one minute
(tidal volume x respiratory rate = minute volume)
Define:
dead air space
air that occupies the airway but that does not actually reach the area of gas exchange
Explain:
how respirations are controlled
in the brain by the medulla oblongata
Define:
plasma oncotic pressure
the pull exerted by large proteins in the plasma portion of blood that tends to pull water from the body into the bloodstream
Define:
hydrostatic pressure
the pressure that tends to push water out of blood vessels
Define:
stretch receptors
sensors in blood vessels that identify internal pressure
Define:
loss of tone
(blood vessel dysfunction)
vessels lose ability to constrict and dilate
Describe:
effect of loss of tone
(blood vessel dysfunction)
results in blood pressure drop
Describe:
significance of excessive permeability
(blood vessel dysfunction)
capillaries become overly “leaky” (allows too much fluid to flow out of walls)
Explain:
significance of SVR
(blood vessel dysfunction)
pressure too high inside vessels
major risk factor in stroke and heart disease
(SVR is systemic vascular resistance)