Chapter 7 - Membrane Structure and Function Flashcards

1
Q

list the components of membranes

A

lipids, carbohydrates, proteins

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2
Q

list the functions of membranes

A

selective permeability barrier, compartmentalization of function, energy transduction, transport (water and solutes), site of some enzymatic activity, communication, intercellular joining, anchorage

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3
Q

describe the fluid mosaic model of membranes

A

membrane components and functions are asymmetric

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4
Q

define membrane fluidity

A

movement of membrane components (phospholipids and proteins)

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5
Q

list the 4 types of movement of phospholipids

A

lateral movement, rotation, flexing of fatty acids, flip-flop transverse diffusion

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6
Q

what is the importance of membrane fluidity?

A

important for basic cell processes to occur

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7
Q

what happens when membranes are too fluid?

A

loss of structural organization and mechanical support - membranes leak

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8
Q

what happens when membranes are too rigid?

A

mobility is poor - membranes leak

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9
Q

list the factors that affect membrane fluidity

A

temperature, lipid composition

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10
Q

define selective permeability

A

allow some things to cross but not others - eg phospholipid bilayers allow water to cross but not all solutes

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11
Q

how do hydrophobic molecules pass through the phospholipid bilayer?

A

simple diffusion

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12
Q

how do small, uncharged, polar molecules pass through the phospholipid bilayer?

A

transport proteins help them cross

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13
Q

how do large, uncharged, polar molecules pass through the phospholipid bilayer?

A

transport proteins are required to help them cross

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14
Q

how do inorganic and organic ions pass through the phospholipid bilayer?

A

transport proteins are required to help them cross

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15
Q

passive transport definition

A

diffusion of a substance across a membrane with no energy investment

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16
Q

define diffusion

A

spontaneous movement of particles of any kind from where they are more concentrated to where they are less concentrated

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17
Q

define concentration gradient

A

increase or decrease in the density of a chemical substance in an area

18
Q

define osmosis

A

simple diffusion of free water across a selectively permeable membrane; moves from areas of low concentration of solute to high concentration to even out the concentration across the membrane

19
Q

define an osmole

A

amount of substance that results in Avogadro’s number of particles when placed in solution

20
Q

define osmotic pressure

A

a measure of the tendency of a solution to take up water when separated from pure water by a selectively permeable membrane; the amount of pressure that will just stop the flow of water

21
Q

define tonicity

A

the ability of a solution to cause a cell within it to gain or lose water

22
Q

what does it mean to be isosmotic with a medium fluid?

A

the same osmotic pressure as the medium

23
Q

what does it mean to be hyperosmotic with a medium fluid?

A

osmotic concentration is higher than the medium

24
Q

what does it mean to be hyposmotic with a medium fluid?

A

osmotic concentration is lower than the medium

25
what does it mean to be isotonic with a solution?
have the same solute concentration
26
what does it mean to be hypertonic with a solution?
the one with a greater solute concentration
27
what does it mean to be hypotonic with a solution?
the one with a lower solute concentration
28
define facilitated diffusion
passive transport mediated by channel proteins or carrier proteins
29
explain how channel proteins work
possess a hydrophilic channel through which atomic ions and some small molecules can pass; some are open all the time, others are gated
30
explain how carrier proteins work
undergo a shape change which takes small ions or molecules across
31
define active transport
movement of a substance across a membrane, through a transport protein, against a chemical or electrochemical gradient; requires energy input and is powered by ATP (or cotransport with a substance moving down its gradient)
32
define exocytosis
vesicular removal of molecules to the extracellular fluid
33
define constitutive exocytosis
ubiquitous and continuous, supplies proteins and lipids to the plasma membrane, secretes many molecules from the cell
34
define regulated exocytosis
operates in cells specialized for secretion, membrane fusion occurs only in response to extracellular signal
35
define membrane fusion
when membranes fuse with each other, the orientation of the leaflets remains the same
36
define endocytosis
vesicular uptake of molecules from the extracellular fluid
37
define phagocytosis
uptake of large, bulky material
38
define pinocytosis
non-specific uptake of fluid from extracellular fluid; occurs almost continuously in most cells
39
define receptor-mediated endocytosis
uptake of specific molecules from extracellular fluid
40
what builds the membrane?
the endoplasmic reticulum and Golgi apparatus