Chapter 7 - Membrane Structure and Function Flashcards

1
Q

list the components of membranes

A

lipids, carbohydrates, proteins

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2
Q

list the functions of membranes

A

selective permeability barrier, compartmentalization of function, energy transduction, transport (water and solutes), site of some enzymatic activity, communication, intercellular joining, anchorage

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3
Q

describe the fluid mosaic model of membranes

A

membrane components and functions are asymmetric

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4
Q

define membrane fluidity

A

movement of membrane components (phospholipids and proteins)

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5
Q

list the 4 types of movement of phospholipids

A

lateral movement, rotation, flexing of fatty acids, flip-flop transverse diffusion

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6
Q

what is the importance of membrane fluidity?

A

important for basic cell processes to occur

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7
Q

what happens when membranes are too fluid?

A

loss of structural organization and mechanical support - membranes leak

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8
Q

what happens when membranes are too rigid?

A

mobility is poor - membranes leak

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9
Q

list the factors that affect membrane fluidity

A

temperature, lipid composition

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10
Q

define selective permeability

A

allow some things to cross but not others - eg phospholipid bilayers allow water to cross but not all solutes

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11
Q

how do hydrophobic molecules pass through the phospholipid bilayer?

A

simple diffusion

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12
Q

how do small, uncharged, polar molecules pass through the phospholipid bilayer?

A

transport proteins help them cross

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13
Q

how do large, uncharged, polar molecules pass through the phospholipid bilayer?

A

transport proteins are required to help them cross

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14
Q

how do inorganic and organic ions pass through the phospholipid bilayer?

A

transport proteins are required to help them cross

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15
Q

passive transport definition

A

diffusion of a substance across a membrane with no energy investment

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16
Q

define diffusion

A

spontaneous movement of particles of any kind from where they are more concentrated to where they are less concentrated

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17
Q

define concentration gradient

A

increase or decrease in the density of a chemical substance in an area

18
Q

define osmosis

A

simple diffusion of free water across a selectively permeable membrane; moves from areas of low concentration of solute to high concentration to even out the concentration across the membrane

19
Q

define an osmole

A

amount of substance that results in Avogadro’s number of particles when placed in solution

20
Q

define osmotic pressure

A

a measure of the tendency of a solution to take up water when separated from pure water by a selectively permeable membrane; the amount of pressure that will just stop the flow of water

21
Q

define tonicity

A

the ability of a solution to cause a cell within it to gain or lose water

22
Q

what does it mean to be isosmotic with a medium fluid?

A

the same osmotic pressure as the medium

23
Q

what does it mean to be hyperosmotic with a medium fluid?

A

osmotic concentration is higher than the medium

24
Q

what does it mean to be hyposmotic with a medium fluid?

A

osmotic concentration is lower than the medium

25
Q

what does it mean to be isotonic with a solution?

A

have the same solute concentration

26
Q

what does it mean to be hypertonic with a solution?

A

the one with a greater solute concentration

27
Q

what does it mean to be hypotonic with a solution?

A

the one with a lower solute concentration

28
Q

define facilitated diffusion

A

passive transport mediated by channel proteins or carrier proteins

29
Q

explain how channel proteins work

A

possess a hydrophilic channel through which atomic ions and some small molecules can pass; some are open all the time, others are gated

30
Q

explain how carrier proteins work

A

undergo a shape change which takes small ions or molecules across

31
Q

define active transport

A

movement of a substance across a membrane, through a transport protein, against a chemical or electrochemical gradient; requires energy input and is powered by ATP (or cotransport with a substance moving down its gradient)

32
Q

define exocytosis

A

vesicular removal of molecules to the extracellular fluid

33
Q

define constitutive exocytosis

A

ubiquitous and continuous, supplies proteins and lipids to the plasma membrane, secretes many molecules from the cell

34
Q

define regulated exocytosis

A

operates in cells specialized for secretion, membrane fusion occurs only in response to extracellular signal

35
Q

define membrane fusion

A

when membranes fuse with each other, the orientation of the leaflets remains the same

36
Q

define endocytosis

A

vesicular uptake of molecules from the extracellular fluid

37
Q

define phagocytosis

A

uptake of large, bulky material

38
Q

define pinocytosis

A

non-specific uptake of fluid from extracellular fluid; occurs almost continuously in most cells

39
Q

define receptor-mediated endocytosis

A

uptake of specific molecules from extracellular fluid

40
Q

what builds the membrane?

A

the endoplasmic reticulum and Golgi apparatus