Chapter 7-Complementation Flashcards

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1
Q

No complementation

A

When both parents carry a mutation on the same gene. F1 generation will show mutant geneotype

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2
Q

complementation

A

mutations are on different genes therefore F1 generation will not show mutant phenotype

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3
Q

complementation test

A

used to determine whether two mutations that cause the same phenotype are mutations in the same gene or in different genes. Can only be used for recessive mutations

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4
Q

auxotroph

A

an organism, such as a strain of bacteria, that has lost the ability to synthesis certain substances required for its growth and metabolism

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5
Q

prototroph

A

a wild type cell that can grow on minimal medium alone

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6
Q

Transition

A

When one purine (A or G) replaces the other purine

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7
Q

Base substitution

A

When a base at a certain position in one strand of the DNA molecule is replaced by one of the other three bases

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8
Q

Transversion

A

When a purine changes to a pyimidine or vice versa

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9
Q

Inversion

A

A 180 degree rotation of a segment of DNA

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10
Q

Translocation

A

Parts of two non homologous chromosome change places

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11
Q

Deletion

A

Occurs when a block of one or more nucleotide pairs is lost from a DNA molecule

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12
Q

Insertion

A

The addition of one or more nucleotide pairs

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13
Q

Deamination

A

The removal of an amino acid group. Can change cytosine to uracil.

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14
Q

Intercalator

A

Class of chemical mutagens composed of flat planar molecules that can sandwich themselves between successive base pairs and disrupt the machinery of replication, recombination, or repair

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15
Q

Unequal crossing over

A

Change in DNA caused by erroneous recombination in which one homologous chromosome end up with a duplication while the other homologe sustains a deletion

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