Chapter 7:: Biology of Hair Follicles

Question 1

Decapentaplegic (Dpp/BMP), engrailed (en), Homeobox (hox), hedgehog/patched (hh/ptc), notch, ________, and branchless (Fgf) genes are all critical for hair follicle and vertebrate development in general

Answer 1

wingless/ armadillo (wg/wnt/catenin)

Question 2

The first hairs formed are ________, which are nonpig- mented, soft, and fine.

Answer 2

lanugo hairs

Question 3

means loss of hair

Answer 3

alopecia

Question 4

_______ a type of homeobox gene, is responsible for dorsal- ventral patterning

Answer 4

Engrailed

Question 5

Types of Hair

Answer 5

Laguno
Vellus
Terminal
Miniaturized

Question 6

___________ occurs where the inner root sheath begins to slough. Des- moglein expression markedly changes here as well, and trichilemmal or pilar cysts retain these characteristics

Answer 6

Trichilemmal keratinization

Question 7

The Huxley layer is two to four cell layers thick and keratinizes above the Henle layer at the region known as ______________.

Answer 7

Adamson fringe

Question 8

nside the cuticle, the cortex com- prises the bulk of the shaft and contains melanin. The cortex is arranged in large cable-like structures called ___________.

Answer 8

macrofibrils

Question 9

KGF means

Answer 9

keratinocyte growth factor

Question 10

hair follicle and consists of an inner basement membrane called the __________ and an outer connective tissue sheath.

Answer 10

hyaline or vitreous (glassy) membrane