Chapter 7

Question 1

Labile cell populations are cells that _____ and are found in areas like the ___

Answer 1

divide continuously

gut

Question 2

Stabile cell populations are cells that

Answer 2

have limited cell division

Question 3

Permanent cell populations have

Answer 3

no ability to divide

Question 4

_____: Localized areas of dysregulated growth

Answer 4

dysplasia

Question 5

A solid tumor type is one that is

Answer 5

embedded in host tissue and is not as bad as invasive growth which penetrates into new tissue.

Question 6

Invasive tumor type is one that has

Answer 6

grown into a new tissue, makes metastitization more likely.

Question 7

Well-circumscribed Tumor =

Answer 7

one with a clear border.

Question 8

Grade refers to

Answer 8

how closely cancer resembles host tissue.

Question 9

A secondary site is

Answer 9

When cancer has metastisized to a new area. Cancer tissue won’t resemble new surrounding tissue.

Question 10

A polyp or papilloma is a malignant/benign tumor usually associated with _____

Answer 10

benign

infection

Question 11

A malignant tumor derived from epitheial cells

Answer 11

carcinoma

Question 12

Prefix:
Neuro
Osteo
Myo

Answer 12

nerve
bone
muscle

Question 13

Prefix:
Adeno
Angio
Lipo

Answer 13

gland
vessels (non specific)
Fat

Question 14

Teratoma

Answer 14

A tumor of mixed cell components

Question 15

A malignant tumor arising from connective and supportive tissue

Answer 15

sarcoma

Question 16

Metaplasia:

Answer 16

Conversion of differentiated tissue type into another.

Question 17

An insitu carcinoma means

Answer 17

Tumor occupies full thickness of epithelium

Question 18

Cervical intraepithelial neoplasia (CIN):

Answer 18

Precancerous condition characterised by vervical dysplasia in mucous of cervix.

Question 19

Actitinic keratosis:

Answer 19

warty, precancerous proliferation of squamous cells in sun damaged skin of elders.

Question 20

____: A white patch of hyper-plastic and usually atypical squamous epithelium on the oral mucous or genital tract mucous.

Answer 20

Leukoplakia

Question 21

Angiogenesis is the formation of ____ ____

Answer 21

new vessels

Question 22

Proto oncogenes:
Normal function:
Malfunction:

Answer 22

Normal function: Promotes normal cell growth

Malfunction: Point mutation, amplification, or translocation forms an oncogene, resulting in unrestrained cell growth.

Question 23

Tumor suppressor genes:
Normal function:
Malfunction:

Answer 23

Normal function: Inhibit cell proliferation

Malfunction: Both genes inactivated in same cell promotes cell proliferation

Question 24

DNA Repair genes:
Normal function:
Malfunction:

Answer 24

Normal function: Correct errors in DNA duplication

Malfunction: Gene inactivation increases mutation rate

Question 25

How many tumor repressor genes must fail for cancer?

Answer 25

both, there are two alleles

Question 26

____ loop refers to many cancers (especially brain) ability to keep replicating

Answer 26

autocrine

Question 27

Pap smear, frozen section, and tests for CEA are tests for

Answer 27

screening cancer

Question 28

Alpha fetoprotein can indicate

Answer 28

neural tube defect

Question 29

HCG can diagnose

Answer 29

testicular cancer

Question 30

____: causing cell death

Answer 30

cytotoxic