Chapter 7 Flashcards
Labile cell populations are cells that _____ and are found in areas like the ___
divide continuously
gut
Stabile cell populations are cells that
have limited cell division
Permanent cell populations have
no ability to divide
_____: Localized areas of dysregulated growth
dysplasia
A solid tumor type is one that is
embedded in host tissue and is not as bad as invasive growth which penetrates into new tissue.
Invasive tumor type is one that has
grown into a new tissue, makes metastitization more likely.
Well-circumscribed Tumor =
one with a clear border.
Grade refers to
how closely cancer resembles host tissue.
A secondary site is
When cancer has metastisized to a new area. Cancer tissue won’t resemble new surrounding tissue.
A polyp or papilloma is a malignant/benign tumor usually associated with _____
benign
infection
A malignant tumor derived from epitheial cells
carcinoma
Prefix:
Neuro
Osteo
Myo
nerve
bone
muscle
Prefix:
Adeno
Angio
Lipo
gland
vessels (non specific)
Fat
Teratoma
A tumor of mixed cell components
A malignant tumor arising from connective and supportive tissue
sarcoma
Metaplasia:
Conversion of differentiated tissue type into another.
An insitu carcinoma means
Tumor occupies full thickness of epithelium
Cervical intraepithelial neoplasia (CIN):
Precancerous condition characterised by vervical dysplasia in mucous of cervix.
Actitinic keratosis:
warty, precancerous proliferation of squamous cells in sun damaged skin of elders.
____: A white patch of hyper-plastic and usually atypical squamous epithelium on the oral mucous or genital tract mucous.
Leukoplakia
Angiogenesis is the formation of ____ ____
new vessels
Proto oncogenes:
Normal function:
Malfunction:
Normal function: Promotes normal cell growth
Malfunction: Point mutation, amplification, or translocation forms an oncogene, resulting in unrestrained cell growth.
Tumor suppressor genes:
Normal function:
Malfunction:
Normal function: Inhibit cell proliferation
Malfunction: Both genes inactivated in same cell promotes cell proliferation
DNA Repair genes:
Normal function:
Malfunction:
Normal function: Correct errors in DNA duplication
Malfunction: Gene inactivation increases mutation rate
How many tumor repressor genes must fail for cancer?
both, there are two alleles
____ loop refers to many cancers (especially brain) ability to keep replicating
autocrine
Pap smear, frozen section, and tests for CEA are tests for
screening cancer
Alpha fetoprotein can indicate
neural tube defect
HCG can diagnose
testicular cancer
____: causing cell death
cytotoxic
