Chapter 6 Flashcards
Humoral immunity
Immunity associated with formation of antibodies produced by plasma cells.
Cell-mediated immunity
Immunity associated with population of sensitized lymphocytes.
______ immunity is associated with the production of antibodies, soluble proteins of the immunoglobulin class. Antibodies circulate in the blood and body fluids and function by binding to and eliminating foreign material
Humoral
B lymphosites are made in
the bone
A lymphocyte that differentiates into plasma cells and is associated with humoral immunity
B lymphocyte
Lymphocyte binding strength is random in many ways because
the ones strong enough to bind to our own HLA self destruct to prevent autoimmune disease, while the ones that can’t bind to anything self destruct. What’s left is the middle that can bind with a wide variety of antigens.
Type 1 T cells effect
CD8+ = cytoxic
These effect viral cells and potentially cancer
Type 2 T cells effect
CD4+ = Thelper
Thelper 1 cells
mediate inflammation via the secretion of a number of pro-inflammatory cytokines, protect against intracellular pathogens, and play a role in the production of delayed hypersensitive reactions
Thelper 2 cells
They provide aid for humoral Bcell mediated immunity and antibody production
Natural killer (NK) cells
part of the innate immune system, but functions are regulated by the adaptive immune system. They make up 10% of circulating lymphocytes.
Bcells gives rise to
plasma cells which secrete antigens
Memory bcells are created
after second exposure to antigen
Memory b cells make ____ cells faster then the first time
plasma cells
Interferons are a type of ____ and act as a broud spectrum ____ ____
Cytokine
antiviral agent
