chapter 7 Flashcards
1
Q
SN2
A
- one step
- second order kinetics
- methy halide > 1 > 2 > 3
- rate = k[RX][Nu]
- backside attack of nuc
- inversion
- stronger nuc favored (-)
- better LG = faster rxn
- aprotic solvents
2
Q
SN1
A
- two steps
- first order kinetics
- 3 > 2 > 1 > methly
- carbocation intermediate
- racemization @ SC
- better LG = faster rxn
- protic solvents (O or N bonded to Hydrogen)
- SHIFT CAN OCCUR
3
Q
rate determining step for SN1?
A
breaking the bond between the carbon and LG to form carbocation (endo)
4
Q
does LG affect SN1 reaction rate?
A
no
5
Q
Leaving group trends
A
- best LG is weakest base
- LG ability increases from L-R and down a column
6
Q
Nucleophilicity trends
A
- same as basicity
- decreases from L-R
- decreases down column for APROTIC
- increases down column for PROTIC
7
Q
steric hinderance (nucleophilicity vs basicity)
A
it decreases nucleophilicty but not basicity
8
Q
carbocations are stabalized by:
A
- electro-donating inductive effects
2. hyperconjugation
