Chapter 62 Dermatomyositis

Question 1

bimodal distribution of dermatomyositis

Answer 1

5-14 y.o.

45-64 y.o.

Question 2

gottron sign

Answer 2

macular erythema over

olecranon
ip
medial malleoli
pattelae

Question 3

cutaneous clue to the possible presence of interstitial lung disease

Answer 3

mechanic’s hands

Question 4

ovoid palatal arch

Answer 4

associated with anti transcriptional factor 1 gamma anti-TIF1

Question 5

most common pulmonary manifestation of DM

Answer 5

ILD

- also leading cause of morbidity and mortality in DM

Question 6

most common radiographic and histologic of ILD in DM

Answer 6

nonspecific interstitial pneumonia

Question 7

antibodies associated with higher risk for ILd

Answer 7

antisynthetase and anti MDA5

Question 8

associated with increase risk for malignancy in DM

Answer 8

increasing age
male gender
cutaneous necrosis
dysphagia
rapid onset of myositis

Question 9

protective factor for malignancy in DM

Answer 9

ILD
raynauds
arthritis

Question 10

first line agent for myositis

Answer 10

oral steroid

methotrexate

Question 11

first line oral agent for ILD

Answer 11

mycophenolate mofetil

Question 12

first line for cutaneous DM

Answer 12

antimalarials

Question 13

single most effective treatment for cutaneous DM

Answer 13

IVIg

2g/kg/month divided into 3-5days