Chapter 60 - Skin Disorders

Question 1

Corticosteroids

• hydrocortisone

Answer 1

 hydrocortisone
• MOA: Reduces inflammation
• Use: Inflammatory dermatologic conditions
• AE: Stinging at site, thinning of skin (face/genitals)  do not recommend using for more than 3-5 days on face or genitals
• Do not cover with tight bandages or occlusive dressings unless instructed to do so (accelerates the rate of absorption)

Question 2

Retinoids

• isotretinoin (Accutane)

Answer 2

o Retinoids
 isotretinoin (Accutane)
 MOA: Suppress sebum production, inhibit comedone formation and inflammation
 Use: Nodular acne
 AE: Dermatologic effects, GI effects, musculoskeletal effects, metabolic effects, psychiatric effects, etc
 BBW: Pregnancy category X (must register with iPLEDGE program); will cause fetal anomalies, must have a license to prescribe this med, must be within 2 weeks of a negative pregnancy test, must have contraception contract/must either be on contraception or not having intercourse

Question 3

Sunscreen

Answer 3

Used for UV light protection (use at least 30 SPF or higher)

Question 4

Emollients

Answer 4

Itchy or dry skin

Question 5

Keratolytics

Answer 5

Treat keratinizing cells (anti-aging)

Question 6

Antiseptics

Answer 6

Used to treat infections, will inhibit bacterial growth

Question 7

Benzoyl peroxide

Answer 7

Used to treat acne